Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

Glucose-responsive insulin delivery systems that mimic pancreatic endocrine function could
enhance health and improve quality of life for people with type 1 and type 2 diabetes with …

Insulin therapy is necessary to regulate blood glucose levels for people with type 1 diabetes
and commonly used in advanced type 2 diabetes. Although subcutaneous insulin …

The intrinsic properties of therapeutic proteins generally present a major impediment for
transdermal delivery, including their relatively large molecule size and susceptibility to …

A bioinspired glucose-responsive insulin delivery system for self-regulation of blood glucose
levels is desirable for improving health and quality of life outcomes for patients with type 1 …

The advancement of drug delivery devices is critical for the individualization of patient
treatment and the improvement of healthcare. Here, we introduce the 3DMNMEMS, a novel …

Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

We describe layer-by-layer (LbL) buildup and pH-responsive behavior of multilayer films of
alginate/chitosan/alginate-modified silica nanocapsules (SNCs) and chitosan (CS) …

Microneedles are one of the most prominent approaches capable of physically disrupting
the stratum corneum without devastating the deeper tissues to deliver both small molecules …