Diastereodivergence in catalytic asymmetric conjugate addition of carbon nucleophiles

B Kim, H Lee, I Song, SY Lee - Chemical Society Reviews, 2025 - pubs.rsc.org
Catalytic asymmetric conjugate additions of carbon nucleophiles have emerged as a potent
tool for constructing multi-stereogenic molecules with precise stereochemical control. This …

Trifluoroethanol promoted formal nucleophilic substitution of indol-2-yl diaryl methanol for the synthesis of tetraarylmethanes

C Nian, R Yu, Z Han, Y Bai, J Wang, J Sun… - Chemical …, 2024 - pubs.rsc.org
The synthesis of tetraarylmethanes has long been a challenge in the field of synthetic
chemistry. In this study, a series of tetraarylmethanes were successfully synthesized through …

Sulfonated asphaltene as a highly efficient catalyst for the Mannich reaction with excellent diastereoselectivity and recyclability

N Habibnejad, N Azizi, M Hajibeygi - Scientific Reports, 2024 - nature.com
This study investigates the repurposing of asphaltene, a petroleum waste product, as a
catalyst for organic reactions. Sulfonated asphaltene was synthesized and evaluated for its …

Tungsten-catalyzed stereodivergent isomerization of terminal olefins

TC Jankins, CZ Rubel, HC Ho, R Martin-Montero… - Chemical …, 2025 - pubs.rsc.org
Catalytic alkene isomerization is a powerful synthetic strategy for preparing valuable internal
alkenes from simple feedstocks. The utility of olefin isomerization hinges on the ability to …

A stereodivergent multicomponent approach for the synthesis of C–N atropisomeric peptide analogues

NJ Roper, ADG Campbell, PG Waddell, AK Brown… - Chemical …, 2024 - pubs.rsc.org
A four-component Ugi reaction is described for the stereoselective synthesis of novel C–N
atropisomeric peptide analogues. Using this approach, a combination of simple, readily …

Solvent-Controlled Diastereodivergent Synthesis of Hexahydropyrrolo[2,1-a]isoquinolines through Pd/C-Catalyzed Dehydrogenative [3 + 2] Cycloaddition

JC Lu, H Bai, YH Huang, ZY Wang… - The Journal of …, 2024 - ACS Publications
A Pd/C-catalyzed dehydrogenative [3+ 2] cycloaddition is described for the
diastereoswitchable synthesis of hexahydropyrrolo [2, 1-a] isoquinolines by altering …