Age‐related hearing loss: Why we need to think about sex as a biological variable

LS Nolan - Journal of neuroscience research, 2020 - Wiley Online Library
It has long been known that age‐related hearing loss (ARHL) is more common, more
severe, and with an earlier onset in men compared to women. Even in the absence of …

Auditory function and dysfunction: estrogen makes a difference

A Delhez, P Lefebvre, C Péqueux, B Malgrange… - Cellular and Molecular …, 2020 - Springer
Estrogen is the major female hormone involved in reproductive functions, but it also exerts a
variety of additional roles in non-reproductive organs. In this review, we highlight the …

[HTML][HTML] Sex differences in hearing: Probing the role of estrogen signaling

BZ Shuster, DA Depireux, JA Mong… - The Journal of the …, 2019 - pubs.aip.org
Hearing loss is the most common form of sensory impairment in humans, with an anticipated
rise in incidence as the result of recreational noise exposures. Hearing loss is also the …

Estradiol protects against noise-induced hearing loss and modulates auditory physiology in female mice

B Shuster, R Casserly, E Lipford, R Olszewski… - International journal of …, 2021 - mdpi.com
Recent studies have identified sex-differences in auditory physiology and in the
susceptibility to noise-induced hearing loss (NIHL). We hypothesize that 17β-estradiol (E2) …

Prevalence of and risk factors for tinnitus and tinnitus-related handicap in a college-aged population

IS Bhatt - Ear and hearing, 2018 - journals.lww.com
Objective: Tinnitus is a common otological condition that affects almost 10% of US adults.
Research suggests that college students are vulnerable to tinnitus and hearing loss as they …

Evaluation of cochlear activity in normal-hearing musicians

NJ Washnik, IS Bhatt, SL Phillips, D Tucker, S Richter - Hearing research, 2020 - Elsevier
Objective The present study compared wave I amplitude of auditory brainstem responses
(ABRs), a potential indicator of cochlear synaptopathy, among musicians and non-musicians …

Analysis of audiometric notch as a noise-induced hearing loss phenotype in US youth: data from the National Health And Nutrition Examination Survey, 2005–2010

IS Bhatt, O Guthrie - International journal of audiology, 2017 - Taylor & Francis
Objective: Bilateral audiometric notch (BN) at 4000–6000 Hz was identified as a noise-
induced hearing loss (NIHL) phenotype for genetic association analysis in college-aged …

Association analysis of candidate gene polymorphisms and audiometric measures of noise-induced hearing loss in young musicians

IS Bhatt, R Dias, N Washnik, J Wang… - Otology & …, 2020 - journals.lww.com
Methods: The study analyzed a database by Phillips et al.(Feasibility of a bilateral 4000–
6000 Hz notch as a phenotype for genetic association analysis. Int J Audiol 2015; 54: 645 …

Galectin-3 protects auditory function in female mice

C Zhang, HJ Adler, S Manohar, R Salvi, W Sun, M Ye… - Hearing Research, 2022 - Elsevier
Sex differences in the development of sensorineural hearing loss have been recognized in
various inner ear disorders, but the molecular basis for such differences is poorly …

Evaluation of dichotic listening performance in normal-hearing, noise-exposed young females

IS Bhatt, J Wang - Hearing research, 2019 - Elsevier
Recent animal studies have shown that intense noise exposures that produce robust
temporary threshold shift (TTS) can inflict irreversible damage to the synaptic connections …