Synthetic organic chemistry has witnessed a plethora of functionalization and
defunctionalization strategies. In this regard, C− H functionalization has been at the forefront …

Sequential multicomponent C–H bond addition is a powerful approach for the rapid,
modular generation of molecular complexity in a single reaction. In this approach, C–H …

Herein, we disclose an efficient cobalt-catalyzed enantioselective C–H activation and
annulation of benzamides with alkenes. This transformation is facilitated via the …

Difunctionalization of olefins offers an attractive approach to access complex chiral
structures. Reported herein is the design of N-protected O-allylhydroxyamines as …

Over the last decade, high-valent cobalt catalysis has earned a place in the spotlight as a
valuable tool for C–H activation and functionalization. Since the discovery of its unique …

Ready availability, low cost and low toxicity of cobalt salts have redirected the attention of
researchers away from noble metals, such as Pd, Rh, and Ir, towards Co in the field of C–H …

Catalytic enantioselective C–H functionalization has recently become a tool for the creation
of stereogenic centers. The steep increase in molecular complexity of multicomponent …

Reported herein is the rhodium-catalyzed enantioselective three-component coupling of
arene, diene, and dioxazolone that occurs via C–H activation en route to allyl intermediate …

Cooperative asymmetric catalysis with hydrogen chloride (HCl) and chiral dual-hydrogen-
bond donors (HBDs) is applied successfully to highly enantioselective Prins cyclization …

Multicomponent reactions (MCRs) are a valuable tool in diversity‐oriented synthesis. Its
application to privileged structures is gaining relevance in the fields of organic and …