Biomembrane-based nanostructures for cancer targeting and therapy: from synthetic liposomes to natural biomembranes and membrane-vesicles

J Wang, M Zhu, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
The translational success of liposomes in chemotherapeutics has already demonstrated the
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …

Phage display screening of therapeutic peptide for cancer targeting and therapy

PE Saw, EW Song - Protein & cell, 2019 - academic.oup.com
Recently, phage display technology has been announced as the recipient of Nobel Prize in
Chemistry 2018. Phage display technique allows high affinity target-binding peptides to be …

Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery

G Zhang, X Li, Q Liao, Y Liu, K Xi, W Huang… - Nature …, 2018 - nature.com
Covalent organic frameworks (COFs) as drug-delivery carriers have been mostly evaluated
in vitro due to the lack of COFs nanocarriers that are suitable for in vivo studies. Here we …

Applications and challenges for use of cell-penetrating peptides as delivery vectors for peptide and protein cargos

M Kristensen, D Birch, H Mørck Nielsen - International journal of …, 2016 - mdpi.com
The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …

Peptide-based drug-delivery systems in biotechnological applications: recent advances and perspectives

D Tesauro, A Accardo, C Diaferia, V Milano, J Guillon… - Molecules, 2019 - mdpi.com
Peptides of natural and synthetic sources are compounds operating in a wide range of
biological interactions. They play a key role in biotechnological applications as both …

Multicellular tumor spheroids (MCTS) as a 3D in vitro evaluation tool of nanoparticles

H Lu, MH Stenzel - Small, 2018 - Wiley Online Library
Multicellular tumor spheroid models (MCTS) are often coined as 3D in vitro models that can
mimic the microenvironment of tissues. MCTS have gained increasing interest in the nano …

Cell penetrating peptides: the potent multi-cargo intracellular carriers

K Kardani, A Milani, S H. Shabani… - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …

Challenge to overcome current limitations of cell-penetrating peptides

GC Kim, DH Cheon, Y Lee - Biochimica et Biophysica Acta (BBA)-Proteins …, 2021 - Elsevier
The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …

Reactive oxygen species-sensitive biodegradable mesoporous silica nanoparticles harboring TheraVac elicit tumor-specific immunity for colon tumor treatment

Y Huang, S Nahar, MDM Alam, S Hu, DW McVicar… - ACS …, 2023 - ACS Publications
Immunotherapy has revolutionized the field of cancer treatment through invigorating robust
antitumor immune response. Here, we report the development of a thera peutic vac cine …

Facile strategy by hyaluronic acid functional carbon dot-doxorubicin nanoparticles for CD44 targeted drug delivery and enhanced breast cancer therapy

J Li, M Li, L Tian, Y Qiu, Q Yu, X Wang, R Guo… - International journal of …, 2020 - Elsevier
A facile approach was developed to synthesize an innovative hyaluronic acid-modified
carbon dot-doxorubicin nanoparticles drug delivery platform. CD44 targeted HA-modified …