Single-neuron neurodegeneration as a degenerative model for Parkinson's disease

S Huenchuguala, J Segura-Aguilar - Neural Regeneration …, 2024 - journals.lww.com
The positive effect of levodopa in the treatment of Parkinson's disease, although it is limited
in time and has severe side effects, has encouraged the scientific community to look for new …

Targeted improvement of plant‐based protein: Genome‐wide association mapping of a lentil (Lens culinaris Medik.) diversity panel

N Johnson, JL Boatwright, W Bridges… - Plants, People …, 2024 - Wiley Online Library
Societal Impact Statement The world is increasingly looking to plant‐based sources to meet
its protein needs. Multiple factors are driving this progression, ranging from nutritional and …

Oleuropein enhances proteasomal activity and reduces mutant huntingtin-induced cytotoxicity

ZN Huang, SY Lee, JM Chen, ZT Huang… - Frontiers in …, 2024 - frontiersin.org
Introduction Huntington's disease (HD) is a hereditary neurodegenerative disorder that
primarily affects the striatum, a brain region responsible for movement control. The disease …

Prepubertal phthalate exposure can cause histopathological alterations, DNA methylation and histone acetylation changes in rat brain

S Koc, E Erdogmus, O Bozdemir… - Toxicology and …, 2025 - journals.sagepub.com
Di-2-(ethylhexyl) phthalate (DEHP) is a phthalate derivative used extensively in a wide
range of materials, such as medical devices, toys, cosmetics, and personal care products …

Can L-Methionine and S-Adenosyl-L-Methionine effectively mitigate scopolamine-induced cognitive and motor deficits in mice?

M Aghababaei, MMA Boojar, M Saberi - PharmaNutrition, 2024 - Elsevier
Motor balance deficits often coincide with cognitive deficits in older adults. Current
medications provide temporary relief with several potential side effects. Essential amino …

Exploratory focused pharmacogenetic testing reveals novel markers associated with risperidone pharmacokinetics in Saudi children with autism

SAR Shilbayeh, IS Adeen, EH Ghanem… - Frontiers in …, 2024 - frontiersin.org
Background: Autism spectrum disorders (ASDs) encompass a broad range of phenotypes
characterized by diverse neurological alterations. Genomic studies have revealed …

[HTML][HTML] Cardioprotective effect of S-adenosyl L-methionine due to antioxidant and anti-inflammatory properties on isoproterenol-induced chronic heart failure in Wistar …

SV Jalgaonkar, R Tripathi, KG Kurhade… - Indian Journal of …, 2024 - journals.lww.com
OBJECTIVES: The development and progression of chronic heart failure (CHF),
hypertrophy, and remodeling strongly correlate with myocardial inflammation and oxidative …

Lentil (Lens culinaris Medik.) Prebiotic Carbohydrates and Protein Quality: Uncovering Genomic Associations and Developing Rapid FTIR Phenotyping Methods

N Johnson - 2022 - tigerprints.clemson.edu
Abstract Lentil (Lens culinaris Medik.) is a cool-season food legume cultivated around the
globe. This pulse crop boasts a rich nutrient profile including high concentrations of prebiotic …

[引用][C] 单神经元神经退行性变作为帕金森病的退行性模型

S Huenchuguala, J Segura-Aguilar - 中国神经再生研究(英文版), 2024