Heart Failure (HF) is a multi-faceted and life-threatening syndrome characterized by
significant morbidity and mortality, poor functional capacity and quality of life, and high costs …

Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused
by infection with group A Streptococcus. The long-term damage to cardiac valves caused by …

Background Rheumatic heart disease affects more than 40.5 million people worldwide and
results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart …

Background Rheumatic heart disease remains an important preventable cause of
cardiovascular death and disability, particularly in low-income and middle-income countries …

The global burden of rheumatic heart disease continues to be significant although it is
largely limited to poor and marginalized populations. In most endemic regions, affected …

Background Rheumatic heart disease (RHD) poses a major disease burden among
disadvantaged populations globally. It results from acute rheumatic fever (ARF), a …

Opinion statement Early recognition of group A streptococcal pharyngitis and appropriate
management with benzathine penicillin using local clinical prediction rules together with …

Autoimmune diseases affect up to 10% of the world's population and, as a whole, they are
far more common in females, although differences exist according to the single disease and …

Methods We conducted a systematic review with the goal of including population-based
data published between 2005 and October 2014. Information on post-streptococcal …

This systematic review and meta-analysis aimed to provide a contemporaneous estimate of
the global burden of rheumatic heart disease (RHD) from echocardiographic population …