Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism

S Badawy, YQ Yang, Y Liu, MA Marawan… - Critical Reviews in …, 2021 - Taylor & Francis
Abstract Ciprofloxacin (CIP)(human use) and enrofloxacin (ENR)(veterinary use) are
synthetic anti-infectious medications that belong to the second generation of …

Safety issues and drug–drug interactions with commonly used quinolones

A Douros, K Grabowski… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Quinolones are widely used antimicrobials with good efficacy and favourable
safety. Recently, forms of quinolone toxicity such as peripheral neuropathy, retinal …

Ciprofloxacin-induced neurotoxicity: evaluation of possible underlying mechanisms

S Ilgin, OD Can, O Atli, UI Ucel, E Sener… - Toxicology …, 2015 - Taylor & Francis
Ciprofloxacin (CPX) is a fluoroquinolone antibiotic used for treating respiratory, urinary tract,
gastrointestinal and abdominal infections. There are only a limited number of studies related …

Gut microbiota and serum metabolomic alterations in modulating the impact of fecal microbiota transplantation on ciprofloxacin-induced seizure susceptibility

S Zou, Y Li, Q Zou, M Yang, H Li, R Niu, H Lai… - Frontiers in …, 2024 - frontiersin.org
Introduction The gut microbiota and the microbiota-gut-brain axis have gained considerable
attention in recent years, emerging as key players in the mechanisms that mediate the …

[HTML][HTML] Tres claves para seleccionar el antibiótico oral adecuado en las infecciones respiratorias

R Menéndez, R Cantón… - Revista Española de …, 2019 - ncbi.nlm.nih.gov
La exacerbación de la enfermedad pulmonar obstructiva crónica y la neumonía adquirida
en la comunidad son las infecciones del tracto respiratorio inferior más frecuentes en la …

A potential mechanism for the ameliorative effect of thymoquinone on pentylenetetrazole-induced kindling and cognitive impairments in mice

AO Abdel-Zaher, HSM Farghaly, MMY Farrag… - Biomedicine & …, 2017 - Elsevier
Cognitive dysfunction is commonly observed in epileptic patients. Pentylenetetrazole (PTZ)
kindling is a well established animal model which simulates clinical epilepsy. This study …

Delafloxacin: an improved fluoroquinolone developed through advanced molecular engineering

M Bassetti, E Righi, D Pecori, G Tillotson - Future Microbiology, 2018 - Taylor & Francis
The emergence of antimicrobial resistance threatens current clinical practice across a range
of infection types. Delafloxacin, a non-zwitterionic fluoroquinolone recently approved by the …

[HTML][HTML] Anticonvulsive effects of licofelone on status epilepticus induced by lithium-pilocarpine in wistar rats: a role for inducible nitric oxide synthase

SM Eslami, MM Moradi, M Ghasemi… - Journal of epilepsy …, 2016 - ncbi.nlm.nih.gov
Background and Purpose Status epilepticus (SE) is a neurological disorder with high
prevalence and mortality rates, requiring immediate intervention. Licofelone is a …

[PDF][PDF] The neuroprotective role of Nigella sativa extract on ciprofloxacin and pentylenetetrazole treated rats

M Abdel-Rahman, NM Arafa… - Afr J Pharm …, 2013 - pdfs.semanticscholar.org
This study aimed to investigate the Nigella sativa seed (NS) neuroprotective effect on
ciprofloxacin (CFX) antibiotic with suggesting neurotoxic effect in rats through the …

[PDF][PDF] Evaluating the protective impact of ginger extract against ciprofloxacin-induced hepatotoxicity in male albino rats

FAE Hemieda, WM El-Kholy… - IOSR Journal of Pharmacy …, 2019 - academia.edu
In the present study, potential protective impact of ginger extract against ciprofloxacin
(CPFX)-induced hepatotoxicity in male rats was investigated. Forty-two adult male albino …