Incorporating machine learning into established bioinformatics frameworks

N Auslander, AB Gussow, EV Koonin - International journal of molecular …, 2021 - mdpi.com
The exponential growth of biomedical data in recent years has urged the application of
numerous machine learning techniques to address emerging problems in biology and …

Representation learning applications in biological sequence analysis

H Iuchi, T Matsutani, K Yamada, N Iwano… - Computational and …, 2021 - Elsevier
Although remarkable advances have been reported in high-throughput sequencing, the
ability to aptly analyze a substantial amount of rapidly generated biological …

A deep fusion matching network semantic reasoning model

W Zheng, Y Zhou, S Liu, J Tian, B Yang, L Yin - Applied Sciences, 2022 - mdpi.com
As the vital technology of natural language understanding, sentence representation
reasoning technology mainly focuses on sentence representation methods and reasoning …

A transformer architecture based on BERT and 2D convolutional neural network to identify DNA enhancers from sequence information

NQK Le, QT Ho, TTD Nguyen… - Briefings in bioinformatics, 2021 - academic.oup.com
Recently, language representation models have drawn a lot of attention in the natural
language processing field due to their remarkable results. Among them, bidirectional …

[PDF][PDF] The accuracy comparison among word2vec, glove, and fasttext towards convolution neural network (cnn) text classification

EM Dharma, FL Gaol, H Warnars, B Soewito - J Theor Appl Inf Technol, 2022 - jatit.org
Feature extraction in the field of Text Processing or Natural Language Processing (NLP) has
its own challenges due to the characteristics of unstructured text. Thus, the selection of the …

BERT-Promoter: An improved sequence-based predictor of DNA promoter using BERT pre-trained model and SHAP feature selection

NQK Le, QT Ho, VN Nguyen, JS Chang - Computational Biology and …, 2022 - Elsevier
A promoter is a sequence of DNA that initializes the process of transcription and regulates
whenever and wherever genes are expressed in the organism. Because of its importance in …

Msu-net: Multi-scale u-net for 2d medical image segmentation

R Su, D Zhang, J Liu, C Cheng - Frontiers in Genetics, 2021 - frontiersin.org
Aiming at the limitation of the convolution kernel with a fixed receptive field and unknown
prior to optimal network width in U-Net, multi-scale U-Net (MSU-Net) is proposed by us for …

DeepIPs: comprehensive assessment and computational identification of phosphorylation sites of SARS-CoV-2 infection using a deep learning-based approach

H Lv, FY Dao, H Zulfiqar, H Lin - Briefings in Bioinformatics, 2021 - academic.oup.com
The rapid spread of SARS-CoV-2 infection around the globe has caused a massive health
and socioeconomic crisis. Identification of phosphorylation sites is an important step for …

DNN-DTIs: Improved drug-target interactions prediction using XGBoost feature selection and deep neural network

C Chen, H Shi, Z Jiang, A Salhi, R Chen, X Cui… - Computers in Biology …, 2021 - Elsevier
Abstract Analysis and prediction of drug-target interactions (DTIs) play an important role in
understanding drug mechanisms, as well as drug repositioning and design. Machine …

Challenges and advances towards the rational design of microalgal synthetic promoters in Chlamydomonas reinhardtii

A Milito, M Aschern, JL McQuillan… - Journal of Experimental …, 2023 - academic.oup.com
Microalgae hold enormous potential to provide a safe and sustainable source of high-value
compounds, acting as carbon-fixing biofactories that could help to mitigate rapidly …