[HTML][HTML] Structured population balances to support microalgae-based processes: Review of the state-of-art and perspectives analysis

A Usai, C Theodoropoulos, F Di Caprio… - Computational and …, 2023 - Elsevier
Abstract Design and optimization of microalgae processes have traditionally relied on the
application of unsegregated mathematical models, thus neglecting the impact of cell-to-cell …

Cellular electrical impedance spectroscopy: an emerging technology of microscale biosensors

W Gu, Y Zhao - Expert review of medical devices, 2010 - Taylor & Francis
Electrical impedance spectroscopy, owing to its label-free, noninvasive and easy
miniaturization nature, has shown great potential in cellular biochemical sensing and cell …

A novel mathematical model to simulate the size-structured growth of microalgae strains dividing by multiple fission

A Concas, M Pisu, G Cao - Chemical Engineering Journal, 2016 - Elsevier
Several microalgae strains are capable to divide by multiple fission, namely they can give
rise to variable number of daughter cells after cytokinesis. Such behavior may have …

A novel population balance model to investigate the kinetics of in vitro cell proliferation: Part I. model development

S Fadda, A Cincotti, G Cao - Biotechnology and Bioengineering, 2012 - Wiley Online Library
In biotechnology and biomedicine reliable models of cell proliferation kinetics need to
capture the relevant phenomena taking place during the mitotic cycle. To this aim, a novel …

Development of a laminar flow bioreactor by computational fluid dynamics

M Israelowitz, B Weyand, S Rizvi… - Journal of …, 2012 - Wiley Online Library
The purpose of this study is to improve the design of a bioreactor for growing bone and other
three‐dimensional tissues using a computational fluid dynamics (CFD) software to simulate …

A novel population balance model to investigate the kinetics of in vitro cell proliferation: Part II. numerical solution, parameters' determination, and model outcomes

S Fadda, A Cincotti, G Cao - Biotechnology and bioengineering, 2012 - Wiley Online Library
Based on the general theoretical model developed in Part I of this work, a series of
numerical simulations related to the in vitro proliferation kinetics of adherent cells is here …

A novel quantitative model of cell cycle progression based on cyclin-dependent kinases activity and population balances

M Pisu, A Concas, G Cao - Computational biology and chemistry, 2015 - Elsevier
Cell cycle regulates proliferative cell capacity under normal or pathologic conditions, and in
general it governs all in vivo/in vitro cell growth and proliferation processes. Mathematical …

Enhanced migration of human bone marrow stromal cells in modified collagen hydrogels

D Guenther, A Oks, M Ettinger, E Liodakis… - International …, 2013 - Springer
Purpose Collagen I hydrogels are widely used as scaffolds for regeneration of articular
cartilage defects. We hypothesised that ingrowth might be improved by removing the …

Numerical rate function determination in partial differential equations modeling cell population dynamics

A Groh, H Kohr, AK Louis - Journal of mathematical biology, 2017 - Springer
This paper introduces a method to solve the inverse problem of determining an unknown
rate function in a partial differential equation (PDE) based on discrete measurements of the …

Mathematical Modelling and Computational Simulation of Mammalian Cell Cycle Progression in Batch Systems

M Pisu, A Concas, G Cao, A Pantaleo - European Journal of Biology and …, 2022 - ejbio.org
Cell cycle and its progression play a crucial role in the life of all living organisms, in tissues
and organs of animals and humans, and therefore are the subject of intense study by …