The use of RNA-based treatments in the field of cancer immunotherapy
M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
P Paramasivam, C Franke, M Stöter, A Höijer… - Journal of Cell …, 2021 - rupress.org
Delivery of exogenous mRNA using lipid nanoparticles (LNPs) is a promising strategy for
therapeutics. However, a bottleneck remains in the poor understanding of the parameters …
therapeutics. However, a bottleneck remains in the poor understanding of the parameters …
Guidelines for mitochondrial RNA analysis
A Jusic, Z Erpapazoglou, LT Dalgaard… - … Therapy-Nucleic Acids, 2024 - cell.com
Mitochondria are the energy-producing organelles of mammalian cells with critical
involvement in metabolism and signaling. Studying their regulation in pathological …
involvement in metabolism and signaling. Studying their regulation in pathological …
Cellular fate of a plant virus immunotherapy candidate
Cowpea mosaic virus (CPMV) is a plant virus that is currently being developed for
intratumoral immunotherapy. CPMV relieves the immune system from tumor-induced …
intratumoral immunotherapy. CPMV relieves the immune system from tumor-induced …