Human secretory IgM: an elusive player in mucosal immunity

E Michaud, C Mastrandrea, N Rochereau, S Paul - Trends in immunology, 2020 - cell.com
Secretory IgMs (SIgMs) were amongst the first identified immunoglobulins. However, their
importance was not fully understood and recent advances have shown they play a key role …

A Protective and Pathogenic Role for Complement During Acute Toxoplasma gondii Infection

PM Sikorski, AG Commodaro, ME Grigg - Frontiers in Cellular and …, 2021 - frontiersin.org
The infection competence of the protozoan pathogen Toxoplasma gondii is critically
dependent on the parasite's ability to inactivate the host complement system. Toxoplasma …

Immune cell landscaping reveals distinct immune signatures of inflammatory bowel disease

X Bai, W Liu, H Chen, T Zuo, X Wu - Frontiers in Immunology, 2022 - frontiersin.org
Determining how the profile of immune cells varies with their disease subtypes and across
lesion locations is critical for understanding the pathogenesis in inflammatory bowel disease …

Immunoglobulin subtype-coated bacteria are correlated with the disease activity of inflammatory bowel disease

Y Masu, Y Kanazawa, Y Kakuta, Y Shimoyama… - Scientific reports, 2021 - nature.com
Immune response involving various immunoglobulin (Ig) isotypes and subtypes to
microbiome is involved in the pathogenesis and disease activity of inflammatory bowel …

Cystatin from filarial parasites suppress the clinical symptoms and pathology of experimentally induced colitis in mice by inducing T-regulatory cells, B1-cells, and …

N Bisht, V Khatri, N Chauhan, R Kalyanasundaram - Biomedicines, 2019 - mdpi.com
Potential alternative therapeutic strategies for immune-mediated disorders are being
increasingly recognized and are studied extensively. We previously reported the therapeutic …

Serum immunoinflammation-related protein complexes discriminate between inflammatory bowel disease and colorectal cancer

YH Sun, J Li, HJ Shu, ZL Li, JM Qian - Clinical and Translational Oncology, 2019 - Springer
Purpose Inflammatory bowel disease (IBD) is an important risk factor for colon cancer. Novel
serum immunoinflammation-related protein complexes (IIRPCs) have shown associations …

Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress

D Martín-Hernández, IL Gutiérrez… - Scientific Reports, 2022 - nature.com
The chronic inflammatory process that characterizes inflammatory bowel diseases (IBD) is
mainly driven by T-cell response to microbial and environmental antigens. Psychological …

[HTML][HTML] Роль В-лимфоцитов и плазматических клеток в патогенезе воспалительных заболеваний кишечника

ОВ Хлынова, ПВ Косарева, ДС Фадеев… - Экспериментальная …, 2023 - cyberleninka.ru
Материалы и методы: Проанализировано 86 литературных источников из баз данных
Scopus, Web of Science, Google scholar, PubMed, а также находящихся в свободном …

Efectos inmunomoduladores de la cistatina de Ascaris lumbricoides sobre los linfocitos B

JJ Rodríguez Cantillo - 2022 - repositorio.unicartagena.edu.co
La actividad aberrante de los linfocitos B se ha asociado con distintas enfermedades
autoinmunitarias como la artritis reumatoide (AR)(1). Esta enfermedad se caracteriza por …

The Role of the Complement in Chronic Intestinal Inflammation

FMM Mohamed - uot.edu.ly
Complement is an important component of the innate immunity that can initiate or sustain
inflammation but can modulate the developing adaptive immune response against invading …