Background Childhood trauma is a common and potent risk factor for developing major
depressive disorder in adulthood, associated with earlier onset, more chronic or recurrent …

The therapeutic alliance is one of the most consistent predictors of therapeutic change,
including symptom reduction and improvement in wellbeing and quality of life, across a …

Background: Low vitamin D levels are associated with a dysregulated hypothalamic-pituitary-
adrenal (HPA) axis and depression but a causal relationship has not been established. This …

Major depressive disorder (MDD) is a prominent psychiatric disorder with a high prevalence
rate. The recent COVID-19 pandemic has exacerbated the already high prevalence of MDD …

Anxiety and mood disorders are prevalent, disabling, and frequently difficult to treat. Such
disorders are often comorbid and share similar characteristics. For more accurate diagnosis …

Background. The aim of the present study was to assess the effects of lavender oil inhalation
on blood pressure, pulse measurements, cortisol levels, depressive mood, and anxiety in …

In modern society, there has been a rising trend of depression and anxiety. This trend
heavily impacts the population's mental health and thus contributes significantly to morbidity …

The cardiovascular system and the central nervous system (CNS) closely cooperate in the
regulation of primary vital functions. The autonomic nervous system and several compounds …

The oxytocin system is involved in psychological functions and interacts with biological
systems that are altered in patients suffering from depressive disorders. This suggests a …

Background Cognitive training is effective in treating neuropsychological impairment in
patients with major depressive disorder (MDD), and virtual reality (VR) is a promising tool to …