The spread of Plasmodium falciparum isolates carrying mutations in the kelch13 (Pfkelch13)
gene associated with artemisinin resistance (PfART-R) in southeast Asia threatens malaria …

Background The devastating public health impact of malaria has prompted the need for
effective interventions. Malaria control gained traction after the introduction of artemisinin …

Malaria elimination relies on detection of Plasmodium falciparum histidine-rich proteins 2/3
(HRP2/3) through rapid diagnostic tests (RDTs) and treatment with artemisinin combination …

Numerous mutations in the Plasmodium falciparum Kelch13 (K13) protein confer resistance
to artemisinin derivatives, the current front-line antimalarial drugs. K13 is an essential …

Panels of informative biallelic single nucleotide polymorphisms (SNPs) have been proposed
to be an economical method to fast-track the population genetic analysis of Plasmodium …

The continuous surveillance of polymorphisms in the kelch propeller domain of Plasmodium
falciparum from Africa is important for the discovery of the actual markers of artemisinin …

Background Timely molecular surveillance of Plasmodium falciparum kelch 13 (k13) gene
mutations is essential for monitoring the emergence and stemming the spread of artemisinin …

Background Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation
approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in …

Background The emergence and spread of multidrug resistance poses a significant risk to
malaria control and eradication goals in the world. There has been no indigenous malaria …

The emergence of artemisinin-resistant parasites since the late 2000s at the border of
Cambodia and Thailand poses serious threats to malaria control globally, particularly in …