Premotor, nonmotor and motor symptoms of Parkinson's disease: a new clinical state of the art

ABRL Silva, RWG de Oliveira, GP Diógenes… - Ageing research …, 2023 - Elsevier
Parkinson's Disease (PD) is a neurodegenerative disorder that affects dopaminergic
neurons in the mesencephalic substantia nigra, causing a progressive clinical course …

Sleep and sleep disorders in people with Parkinson's disease

A Iranzo, VC De Cock, ML Fantini… - The Lancet …, 2024 - thelancet.com
Sleep disorders are common in people with Parkinson's disease. These disorders, which
increase in frequency throughout the course of the neurodegenerative disease and impair …

Quantification analysis of sleep based on smartwatch sensors for Parkinson's disease

YF Ko, PH Kuo, CF Wang, YJ Chen, PC Chuang, SZ Li… - Biosensors, 2022 - mdpi.com
Rapid eye movement (REM) sleep behavior disorder (RBD) is associated with Parkinson's
disease (PD). In this study, a smartwatch-based sensor is utilized as a convenient tool to …

Biosensors toward behavior detection in diagnosis of alzheimer's disease

X Sun, X Sun, Q Wang, X Wang, L Feng… - … in Bioengineering and …, 2022 - frontiersin.org
In recent years, a huge number of individuals all over the world, elderly people, in particular,
have been suffering from Alzheimer's disease (AD), which has had a significant negative …

Pharmacological interventions targeting α-synuclein aggregation triggered REM sleep behavior disorder and early development of Parkinson's disease

L Du, X He, X Fan, X Wei, L Xu, T Liang, C Wang… - Pharmacology & …, 2023 - Elsevier
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized
by elevated motor behaviors and dream enactments in REM sleep, often preceding the …

Parkinson's disease: a narrative review on potential molecular mechanisms of sleep disturbances, REM behavior disorder, and melatonin

MA Samizadeh, H Fallah, M Toomarisahzabi, F Rezaei… - Brain Sciences, 2023 - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative diseases. There is
a wide range of sleep disturbances in patients with PD, such as insomnia and rapid eye …

Nocturia and Sleep in Parkinson's Disease

Ş Diaconu, L Irincu, L Ungureanu, D Țînț… - Journal of Personalized …, 2023 - mdpi.com
Background: Nocturia has a high prevalence in Parkinson's Disease (PD) and is known to
be a bothersome symptom for people with Parkinson's disease (PwPD). Objective: to …

Retinal dysfunction in Parkinson's disease—results of the extended protocol for photopic negative response (PHNR) full-field electroretinogram (ERG)

OA Polat, M Gultekin, H Sener, F Ozer… - Documenta …, 2023 - Springer
Background We investigated whether the photopic negative response (PhNR) in the
electroretinogram (ERG) was affected in Parkinson's disease (PD) patients and whether it …

Personalized assessment of insomnia and sleep quality in patients with Parkinson's disease

Ş Diaconu, C Falup-Pecurariu - Journal of Personalized Medicine, 2022 - mdpi.com
Sleep disturbances are more common in patients with Parkinson's disease (PD) than in the
general population and are considered one of the most troublesome symptoms by these …

[HTML][HTML] SARS-CoV-2 Infection and Alpha-Synucleinopathies: Potential Links and Underlying Mechanisms

JA Motyl, G Gromadzka, GA Czapski… - International Journal of …, 2024 - mdpi.com
Alpha-synuclein (α-syn) is a 140-amino-acid, intrinsically disordered, soluble protein that is
abundantly present in the brain. It plays a crucial role in maintaining cellular structures and …