In the mammalian nervous system, billions of neurons connected by quadrillions of
synapses exchange electrical, chemical and mechanical signals. Disruptions to this network …

Bidirectional interfacing with the nervous system enables neuroscience research, diagnosis,
and therapy. This two-way communication allows us to monitor the state of the brain and its …

The third edition of this besteller covers the latest advancements in this rapidly growing field.
Focusing on analyses and critical evaluation of the subject, this new edition reviews the …

The tumour microenvironment regulates tumour progression and the spread of cancer in the
body. Targeting the stromal cells that surround cancer cells could, therefore, improve the …

Simultaneously measuring the activities of all neurons in a mammalian brain at millisecond
resolution is a challenge beyond the limits of existing techniques in neuroscience. Entirely …

Amide proton transfer (APT) imaging is a type of chemical exchange–dependent saturation
transfer (CEST) magnetic resonance imaging (MRI) in which amide protons of endogenous …

Magnetic resonance imaging (MRI) enables high-resolution non-invasive observation of the
anatomy and function of intact organisms. However, previous MRI reporters of key biological …

In this review we would like to aim at pharmaceuticals engineered on the nanoscale, ie
pharmaceuticals where the nanomaterial plays the pivotal therapeutic role or adds …

We describe a family of calcium indicators for magnetic resonance imaging (MRI), formed by
combining a powerful iron oxide nanoparticle-based contrast mechanism with the versatile …

Using magnetic nanoparticles to absorb alternating magnetic field energy as a method of
generating localized hyperthermia has been shown to be a potential cancer treatment. This …