Foods rich in ellagic tannins are first hydrolyzed into ellagic acid in the stomach and small
intestine, and then converted into urolithins with high bioavailability by the intestinal flora …

Urolithin (Uro) B is a natural compound produced by gut bacteria from ingested ellagitannins
(ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranates …

Genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, loss
of proteostasis, deregulated nutrient-sensing, cellular senescence, stem cell exhaustion …

T memory stem cells (T SCM) display increased self-renewal and prolonged survival
capabilities, thus preventing T cell exhaustion and promoting effective anti-tumor T cell …

Osteoporosis (OP) is characterized by decreased trabecular bone volume and
microarchitectural deterioration in the medullary cavity. Urolithin A (UA) is a biologically …

Background Mediterranean (MED) diet is a rich source of polyphenols, which benefit
adiposity by several mechanisms. We explored the effect of the green-MED diet, twice …

Globally, metabolic diseases are becoming a major public health problem. Herbal
medicines are medicinal materials or preparations derived from plants and are widely used …

Urolithin A (UA) is a gut metabolite derived from ellagic acid. This systematic review
assesses the potential geroprotective effect of UA in humans. In five studies including 250 …

The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …

Inflammatory bowel disease (IBD) is characterized by the upregulation of reactive oxygen
species (ROS) and dysfunction of gut immune system, and microbiota. The conventional …