Recent neuroscience research has established the adult brain as a dynamic organ having a
unique ability to undergo changes with time. Neuroglia, especially microglia and astrocytes …

Various immune cells and cytokines are present in the aftermath of peripheral nerve injuries
(PNI), and coordination of the local inflammatory response is of great significance for the …

Axonal degeneration is a common pathological feature in many acute and chronic
neurological diseases such as spinal cord injury (SCI). SARM1 (sterile alpha and TIR motif …

Although significant advances have been made in synthetic nerve conduits and surgical
techniques, complete regeneration following peripheral nerve injury (PNI) remains far from …

Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …

Peripheral nerve injuries (PNI) are common and often result in lifelong disability. The
peripheral nervous system has an inherent ability to regenerate following injury, yet …

Alzheimer's disease (AD) is a complex neurodegenerative disorder. The pathology is
characterized by the generation of amyloid plaques and neuronal fiber tangles in the brain …

The complexity of the nervous system structure and function, and its slow regeneration rate,
makes it more difficult to treat compared to other tissues in the human body when an injury …

The regenerative capacity of peripheral nerves declines during aging, contributing to the
development of neuropathies, limiting organism function. Changes in Schwann cells prompt …

Leading-edge regenerative medicine can take advantage of improved knowledge of key
roles played, both in stem cell fate determination and in cell growth/differentiation, by …