Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
H2S Donors with Cytoprotective Effects in Models of MI/R Injury and Chemotherapy-Induced Cardiotoxicity
Q Hu, JC Lukesh III - Antioxidants, 2023 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous signaling molecule that greatly influences several
important (patho) physiological processes related to cardiovascular health and disease …
important (patho) physiological processes related to cardiovascular health and disease …
TLRs-JNK/NF-κB pathway underlies the protective effect of the sulfide salt against liver toxicity
Hydrogen sulfide (H2S) is an endogenously gas transmitter signaling molecule with known
antioxidant, anti-inflammatory, and cytoprotective properties. Although accumulating …
antioxidant, anti-inflammatory, and cytoprotective properties. Although accumulating …
Laminaria japonica fucoidan ameliorates cyclophosphamide‐induced liver and kidney injury possibly by regulating Nrf2/HO‐1 and TLR4/NF‐κB signaling pathways
S Tian, X Jiang, Y Tang, T Han - Journal of the Science of Food …, 2022 - Wiley Online Library
BACKGROUND During clinical practice, cyclophosphamide (CTX) can lead to liver and
kidney injury in vivo. In this study, we established a liver and kidney injury model by injecting …
kidney injury in vivo. In this study, we established a liver and kidney injury model by injecting …
Oral delivery of nerolidol alleviates cyclophosphamide-induced renal inflammation, apoptosis, and fibrosis via modulation of NF-κB/cleaved caspase-3/TGF-β …
Cyclophosphamide (CP) is one of the most extensively used antineoplastic drug, but the
nephrotoxicity caused by this drug is a major limiting factor for its use. Nerolidol (NERO) is a …
nephrotoxicity caused by this drug is a major limiting factor for its use. Nerolidol (NERO) is a …
Nrf2/HO-1 as a therapeutic target in renal fibrosis
EHM Hassanein, IM Ibrahim, EK Abd-Alhameed… - Life Sciences, 2023 - Elsevier
Chronic kidney disease (CKD) is one of the most prevalent chronic diseases and affects
between 10 and 14% of the world's population. The World Health Organization estimates …
between 10 and 14% of the world's population. The World Health Organization estimates …
Magnolin alleviates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis via Nrf2/HO-1 signaling pathway
In the present study, we investigated the protective effect of magnolin (MAG) against
oxidative stress induced by cyclophosphamide (CP) and its role in the Nrf2/HO-1 signaling …
oxidative stress induced by cyclophosphamide (CP) and its role in the Nrf2/HO-1 signaling …
A study to assess the health effects of an anticancer drug (cyclophosphamide) in zebrafish (Danio rerio): eco-toxicity of emerging contaminants
Cyclophosphamide (CP) is widely used for treating various kinds of cancer. Because of its
high intake, metabolism and excretion, these anticancer medications have been detected in …
high intake, metabolism and excretion, these anticancer medications have been detected in …
Hydrogen sulfide as a therapeutic option for the treatment of Duchenne muscular dystrophy and other muscle-related diseases
K Kaziród, M Myszka, J Dulak, A Łoboda - Cellular and Molecular Life …, 2022 - Springer
Hydrogen sulfide (H2S) has been known for years as a poisoning gas and until recently
evoked mostly negative associations. However, the discovery of its gasotransmitter functions …
evoked mostly negative associations. However, the discovery of its gasotransmitter functions …
Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP+-Induced SH-SY5Y Cells
X Lai, Y Zhang, J Wu, M Shen, S Yin, J Yan - Neurotoxicity Research, 2023 - Springer
Oxidative stress plays a crucial role in the occurrence and development of Parkinson's
disease (PD). Rutin, a natural botanical ingredient, has been shown to have antioxidant …
disease (PD). Rutin, a natural botanical ingredient, has been shown to have antioxidant …