O Köhler-Forsberg, M Højlund, C Rohde… - Schizophrenia …, 2024 - Elsevier
Background Antipsychotic polypharmacy (APP) is frequent but evidence-based guidelines on reducing APP to antipsychotic monotherapy (APM) are sparse. We aimed to …
E Wagner, JJ Luykx, W Strube… - Expert Review of Clinical …, 2024 - Taylor & Francis
Introduction Developing novel antipsychotic mechanisms of action and repurposing established compounds for the treatment of schizophrenia is of utmost importance to …
The second-generation antipsychotic clozapine is used as a medication for treatment- resistant schizophrenia. It has previously been associated with epigenetic changes in pre …
Abstract Treatment-resistant schizophrenia (TRS) is associated with great disability, functional impairment, and substantial socioeconomic costs. While clozapine is indicated in …