Natural products have been an integral part of sustaining civilizations because of their
medicinal properties. Past discoveries of bioactive natural products have relied on …

Triterpenoids are a large group of natural and synthetic products. This review deals with the
current state of knowledge on their interaction with serum albumin. The binding of drugs to …

Asiatic acid, a triterpenoid compound, has been shown to have anti-inflammatory activity
through the inhibition of the formation of cyclooxygenase-2 (COX-2) in vitro and in vivo. This …

Malaria driven pathophysiology inimically conjoined to systemic inflammation response
cascade in a vicious feed-forward cycle destined to a terrible debilitation or demise of the …

Background Malaria prevention has remained a critical area in the absence of efficacious
vaccines against malaria. Drugs currently used as chemotherapeutics are also used in …

Aim: To evaluate the anticancer activity in vitro and the pharmacokinetic profile of six
synthesized hydrazonic compounds, identified as vanillin 1-phthalazinylhydrazone (VAN-1); …

Obesity is a complex disease involving excessive amounts of body fat due to problems with
lipid metabolism and catalysis by PPARγ and GPR120. It is currently known that full-agonist …

Asiatic acid (AA) and asiaticoside, pentacyclic triterpenoid compounds derived from Centella
asiatica, are known for their biological effects in promoting type I collagen synthesis and …

Antimalarial Phytochemicals: Delineation of the Triterpene Asiatic Acid Malarial Anti-Disease
and Pathophysiological Remedial Activities - Part I | Journal of Infectious Diseases and …

Objective: The aim of this study was to determine the stability interaction of asiatic acid
derivatives (AA) complex with inducible nitric oxide synthase (iNOS) enzyme as an anti …