Background Chemokines play a critical role in orchestrating the distribution and trafficking of
neutrophils in homeostasis and disease. Results The CXCR 4/CXCL 12 chemokine axis has …

The inappropriate retention of neutrophils at inflammatory sites is a major driver of the
excessive tissue damage characteristic of respiratory inflammatory diseases including …

Drug abuse significantly affects the neuroimmune system, which in turn contributes to the
development of addiction. Chemokines, the critical components of neuroimmune factors …

Introduction Stress may pose a serious challenge to immune homeostasis. Stress however
also may prepare the immune system for challenges such as wounding or infection, which …

Purpose Lignin is the most abundant source of aromatic biopolymers and has gained
interest in industrial and biomedical applications due to the reported biocompatibility and …

Chemokine receptor cxcr4 and its ligand cxcl12 have evolved two paralogs in the teleost
lineage. In this study, we have identified four duplicated cxcr4 and cxcl12 genes from …

Hematopoietic stem/progenitor cells (HSPCs) generate the entire repertoire of immune cells
in vertebrates and play a crucial role during infection. Although two copies of CXC motif …

Blood transcriptomics has emerged as a vital tool for tracking the immune system and
supporting disease diagnosis, prognosis, treatment, and research. The present study was …

The TIRAP protein is an adaptor protein in TLR signaling which links TLR2 and TLR4 to the
adaptor protein Myd88. The transcriptomic profiles of zebrafish larvae from a tirap, myd88 …

Fish are a potential source of diverse organic compounds with a broad spectrum of
biological activities. Many fish-derived antimicrobial peptides and proteins are key …