Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Antimicrobial polymeric nanoparticles

SJ Lam, EHH Wong, C Boyer, GG Qiao - Progress in polymer science, 2018 - Elsevier
Currently, infections caused by multidrug-resistant bacteria have reached critical levels.
Thus, various approaches are being explored for the development of new and effective …

Biomimetic antimicrobial polymers: Recent advances in molecular design

C Ergene, K Yasuhara, EF Palermo - Polymer Chemistry, 2018 - pubs.rsc.org
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Antimicrobial cationic polymers: From structural design to functional control

Y Yang, Z Cai, Z Huang, X Tang, X Zhang - Polymer Journal, 2018 - nature.com
Antimicrobial cationic polymers mainly contain two functional components: the cationic
groups and the hydrophobic groups. The antimicrobial activity is influenced by the type …

[HTML][HTML] The ROMP toolbox upgraded

A Leitgeb, J Wappel, C Slugovc - Polymer, 2010 - Elsevier
This article features the current state of research in olefin metathesis polymerization
techniques towards the synthesis of functional polymeric materials. Emphasis is laid on work …

Towards sequence‐controlled antimicrobial polymers: effect of polymer block order on antimicrobial activity

PR Judzewitsch, TK Nguyen… - Angewandte Chemie …, 2018 - Wiley Online Library
Synthetic polymers have shown promise in combating multidrug‐resistant bacteria.
However, the biological effects of sequence control in synthetic antimicrobial polymers are …

Recent advances in ring-opening metathesis polymerization, and application to synthesis of functional materials

S Sutthasupa, M Shiotsuki, F Sanda - Polymer journal, 2010 - nature.com
This article reviews the development of catalysts for ring-opening metathesis polymerization
(ROMP), synthesis of polymers bearing amino acids and peptides by ROMP of …

Will new generations of modified antimicrobial peptides improve their potential as pharmaceuticals?

NK Brogden, KA Brogden - International journal of antimicrobial agents, 2011 - Elsevier
The concept of antimicrobial peptides (AMPs) as potent pharmaceuticals is firmly
established in the literature, and most research articles on this topic conclude by stating that …

Synthetic macromolecules as therapeutics that overcome resistance in cancer and microbial infection

J Tan, J Tay, J Hedrick, YY Yang - Biomaterials, 2020 - Elsevier
Synthetic macromolecular antimicrobials have shown efficacy in the treatment of multidrug
resistant (MDR) pathogens. These synthetic macromolecules, inspired by Nature's …

Recent synthetic transport systems

S Matile, AV Jentzsch, J Montenegro… - Chemical Society Reviews, 2011 - pubs.rsc.org
This critical review covers progress with synthetic transport systems, particularly ion
channels and pores, between January 2006 and December 2009 in a comprehensive …