A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …

Oxidative stress has been implicated as playing a role in neurodegenerative disorders, such
as ischemic stroke, Alzheimer's, Huntington's, and Parkinson's disease. Persuasive …

A colorimetric and fluorescent probe ER-ClO was presented in this work to detect cellular
hypochlorite with high selectivity and sensitivity. With an organelle targeting unit, ER-ClO …

The sarco (endo) plasmic reticulum calcium ATPase (SERCA) is responsible for transporting
calcium (Ca2+) from the cytosol into the lumen of the sarcoplasmic reticulum (SR) following …

Due to the biological and industrial importance of hypochlorous acid, the development of
optical probes for HOCl has been an active research area. Hypochlorous acid and …

In healthy muscle, the rapid release of calcium ions (Ca2+) with excitation–contraction (EC)
coupling, results in elevations in Ca2+ concentrations which can exceed 10-fold that of …

Myeloperoxidase is an important heme enzyme released by activated leukocytes that
catalyzes the reaction of hydrogen peroxide with halide and pseudo-halide ions to form …

Chlorotyrosine, a bio‐marker of hypochlorous acid (HOCl) in vivo, was reported to be
substantially elevated in the Alzheimer's disease (AD) brains. Thus, HOCl might be …

Study Design. An animal study using myeloperoxidase-knockout (MPO-KO) mice to examine
the in vivo role of myeloperoxidase (MPO) in spinal cord injury (SCI). Objective. To clarify the …