Interleukin-22 inhibits apoptosis of gingival epithelial cells through TGF-β signaling pathway during periodontitis
Y Huang, L Zhang, L Tan, C Zhang, X Li, P Wang… - Inflammation, 2023 - Springer
Periodontitis is a chronic inflammatory disease characterized by the destruction of tooth-
supporting tissues. The gingival epithelium is the first barrier of periodontal tissue against …
supporting tissues. The gingival epithelium is the first barrier of periodontal tissue against …
Transcriptional regulators ensuring specific gene expression and decision-making at high TGFβ doses
L Hartmann, P Kristofori, C Li, K Becker… - Life Science …, 2025 - life-science-alliance.org
TGFβ-signaling regulates cancer progression by controlling cell division, migration, and
death. These outcomes are mediated by gene expression changes, but the mechanisms of …
death. These outcomes are mediated by gene expression changes, but the mechanisms of …
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front
YI Chen, SC Tien, YL Ko, CC Chang, MF Hsu… - Cancer gene …, 2024 - nature.com
Tumor invasion is the hallmark of tumor malignancy. The invasive infiltration pattern of tumor
cells located at the leading edge is highly correlated with metastasis and unfavorable patient …
cells located at the leading edge is highly correlated with metastasis and unfavorable patient …
In vitro modelling of anterior primitive streak patterning with human pluripotent stem cells identifies the path to notochord progenitors
M Robles-Garcia, C Thimonier, K Angoura… - …, 2024 - journals.biologists.com
Notochord progenitors (NotoPs) represent a scarce yet crucial embryonic cell population,
playing important roles in embryo patterning and eventually giving rise to the cells that form …
playing important roles in embryo patterning and eventually giving rise to the cells that form …
Modeling Cellular Signaling Variability Based on Single-Cell Data: The TGF-SMAD Signaling Pathway
U Sarma, L Ripka, UA Anyaegbunam… - … Modeling of Signaling …, 2020 - Springer
Nongenetic heterogeneity is key to cellular decisions, as even genetically identical cells
respond in very different ways to the same external stimulus, eg, during cell differentiation or …
respond in very different ways to the same external stimulus, eg, during cell differentiation or …
Modeling Cellular Signaling Variability Based on Single-Cell Data: The TGFβ-SMAD Signaling Pathway
Nongenetic heterogeneity is key to cellular decisions, as even genetically identical cells
respond in very different ways to the same external stimulus, eg, during cell differentiation or …
respond in very different ways to the same external stimulus, eg, during cell differentiation or …
Zellen sind Individualisten—Entscheidungsprozesse auf Einzelzellebene
S Lenhardt, L Hartmann, S Legewie, A Loewer - BIOspektrum, 2024 - Springer
Decision-making is a fundamental aspect of life. However, our understanding of how cells
encode and decode information to enable reliable fate decisions remains limited. Employing …
encode and decode information to enable reliable fate decisions remains limited. Employing …
Investigating SMAD Signaling Dynamics and Function in Single Cells
Z Huang - tuprints.ulb.tu-darmstadt.de
SMAD signaling is crucial for regulating key cellular processes such as differentiation,
proliferation, apoptosis, migration, and extracellular matrix production. The pathway gets …
proliferation, apoptosis, migration, and extracellular matrix production. The pathway gets …