SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

[HTML][HTML] Long COVID: the nature of thrombotic sequelae determines the necessity of early anticoagulation

C Wang, C Yu, H Jing, X Wu, VA Novakovic… - Frontiers in Cellular …, 2022 - frontiersin.org
Many discharged COVID-19 patients affected by sequelae experience reduced quality of life
leading to an increased burden on the healthcare system, their families and society at large …

[HTML][HTML] ISTH guidelines for antithrombotic treatment in COVID‐19

S Schulman, M Sholzberg, AC Spyropoulos… - Journal of Thrombosis …, 2022 - Elsevier
Antithrombotic agents reduce risk of thromboembolism in severely ill patients. Patients with
coronavirus disease 2019 (COVID‐19) may realize additional benefits from heparins …

Pulmonary thrombosis and thromboembolism in COVID-19

HD Poor - Chest, 2021 - Elsevier
COVID-19, the disease responsible for the devastating pandemic that began at the end of
2019, has been associated with a significantly increased risk of pulmonary thrombosis, even …

[HTML][HTML] Standard prophylactic versus intermediate dose enoxaparin in adults with severe COVID‐19: a multi‐center, open‐label, randomized controlled trial

US Perepu, I Chambers, A Wahab, P Ten Eyck… - Journal of Thrombosis …, 2021 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID‐19) is associated with
coagulopathy but the optimal prophylactic anticoagulation therapy remains uncertain and …

The pathogenesis of coronavirus-19 disease

AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …

[HTML][HTML] Dexamethasone in hospitalised COVID-19 patients not on intensive respiratory support

K Crothers, R DeFaccio, J Tate… - European …, 2022 - publications.ersnet.org
Background Dexamethasone decreases mortality in coronavirus disease 2019 (COVID-19)
patients on intensive respiratory support (IRS) but is of uncertain benefit if less severely ill …

Heparin: An old drug for new clinical applications

P Wang, L Chi, Z Zhang, H Zhao, F Zhang… - Carbohydrate …, 2022 - Elsevier
Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week

ME Farkouh, GW Stone, A Lala, E Bagiella… - Journal of the American …, 2022 - jacc.org
Clinical, laboratory, and autopsy findings support an association between coronavirus
disease-2019 (COVID-19) and thromboembolic disease. Acute COVID-19 infection is …

The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?

G Morris, CC Bortolasci, BK Puri, W Marx, A O'Neil… - Cytokine, 2021 - Elsevier
An analysis of published data appertaining to the cytokine storms of COVID-19, H1N1
influenza, cytokine release syndrome (CRS), and macrophage activation syndrome (MAS) …