Further investigations of nitroheterocyclic compounds as potential antikinetoplastid drug candidates

C García-Estrada, Y Pérez-Pertejo… - Biomolecules, 2023 - mdpi.com
Due to the lack of specific vaccines, management of the trypanosomatid-caused neglected
tropical diseases (sleeping sickness, Chagas disease and leishmaniasis) relies exclusively …

[HTML][HTML] Drug resistance in animal trypanosomiases: Epidemiology, mechanisms and control strategies

MA Ungogo, HP de Koning - … Journal for Parasitology: Drugs and Drug …, 2024 - Elsevier
Animal trypanosomiasis (AT) is a complex of veterinary diseases known under various
names such as nagana, surra, dourine and mal de caderas, depending on the country, the …

Synthesis of praseodymium vanadate in deep eutectic solvent medium for electrochemical detection of furaltadone

TW Chen, TS Priya, SM Chen, T Kokulnathan… - Process Safety and …, 2023 - Elsevier
The fabrication of electrode material with unique physiochemical properties is significant to
enhance electrochemical performance. In this work, we synthesized praseodymium …

Yttrium incorporated TiO2 nanoparticles anchored with mesoporous silica as efficient sensor platform for furaltadone detection across diverse matrices

C Ragumoorthy, N Nataraj, TW Chen, SM Chen… - Journal of Alloys and …, 2025 - Elsevier
Furaltadone (FRL), a widely used antipathogenic agent, has raised significant concerns due
to its recognized mutagenic and carcinogenic properties, posing a substantial threat to …

In Vitro and In Vivo Trypanocidal Efficacy of Nitrofuryl- and Nitrothienylazines

HD Janse van Rensburg, DD N'Da, K Suganuma - ACS omega, 2023 - ACS Publications
African trypanosomiasis is a vector-borne disease of animals and humans in the tsetse fly
belt of Africa. Trypanosoma congolense (“nagana”) is the most pathogenic trypanosome in …

[HTML][HTML] In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives

HDJ van Rensburg, DND David… - European Journal of …, 2024 - Elsevier
African trypanosomiasis is a significant vector-borne disease of humans and animals in the
tsetse fly belt of Africa, particularly affecting production animals such as cattle, and thus …

Nitrofurans in natural waters: optimisation and validation of SPE-based method using UHPLC-HRMS techniques

C Efthymiou, V Boti, T Albanis - International Journal of …, 2024 - Taylor & Francis
ABSTRACT A technique employing solid-phase extraction (SPE) coupled with an ultra-high
performance liquid chromatography–high resolution mass spectrometry system was …

[HTML][HTML] In vitro antitrypanosomal activity of synthesized nitrofurantoin-triazole hybrids against Trypanosoma species causing animal African trypanosomosis

A Seetsi, DND David, N Nyembe, K Suganuma… - Experimental …, 2024 - Elsevier
Animal African trypanosomosis (AAT) is a disease caused by Trypanosoma brucei brucei, T.
vivax, T. evansi and T. congolense which are mainly transmitted by tsetse flies (maybe the …

Therapeutic Strategies against Leishmania and Trypanosoma

ALS Santos, IA Rodrigues, CM d'Avila-Levy, CL Sodré… - Pathogens, 2023 - mdpi.com
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma
brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American …

Characterising the Heat Shock Response in Trypanosoma Congolense

M Aelmans - 2022 - search.proquest.com
Trypanosoma congolense causes significant economic burden across Sub-Saharan Africa,
as it is the causative agent of Animal African Trypanosomiasis (AAT), a wasting disease …