Objective To provide a comprehensive analysis of cytokine perturbations in antipsychotic‐
naïve first‐episode psychosis (FEP) populations and assess the relationship between …

In the past decade, there has been an increasing awareness that traumatic brain injury (TBI)
and concussion substantially increase the risk for developing psychiatric disorders. Even …

Background Low-grade inflammation may occur in association with several mental disorders
of early adulthood, though associations with markers of chronic inflammation such as …

As the global burden of mortality from COVID-19 continues to rise, an understanding of who
is most at risk of adverse outcomes is of paramount importance. Pre-existing …

Intravital microscopy (IVM) is a powerful technique that enables imaging of internal tissues at
(sub) cellular resolutions in living animals. Here, we present a silicone-based imaging …

Background Allostatic load (AL) indicates the cumulative impact of stress on homeostatic
mechanisms. Depression and AL have been associated with cognitive deficits, but it is …

Meta-analyses of cross-sectional studies suggest that patients with psychosis have higher
circulating levels of C-reactive protein (CRP) compared with healthy controls; however …

Background Thyroid dysfunction is often reported in patients with major depressive disorder
(MDD) and may be associated with depression severity and psychotic symptoms. We …

Background Major depressive disorder (MDD) is a prevalent psychiatric disorder, with
increasing evidence that patients with MDD display psychotic symptoms. Studies have …

Background It has been reported that childhood trauma and inflammation are associated
with major depressive disorder (MDD) and schizophrenia (SZ), but previous researches …