One dominant hypothesis about the function of the orbitofrontal cortex (OFC) is that the OFC
signals the subjective values of possible outcomes to other brain areas for learning and …

The orbital frontal cortex (OFC) has long been linked to goal-directed, flexible behaviors.
Recent evidence suggests the OFC plays key roles in representing the abstracted structure …

Recording action potentials extracellularly during behavior has led to fundamental
discoveries regarding neural function—hippocampal neurons respond to locations in space …

First theorized by Hebb, neuronal ensembles have provided a framework for understanding
how the mammalian brain operates, especially regarding learning and memory. Neuronal …

The orbitofrontal cortex (OFC) has been implicated in goal-directed planning and model-
based decision-making. One key prerequisite for model-based decision-making is learning …

Schemas are rich and complex knowledge structures about the typical unfolding of events in
a context. For example, a schema of a lovely dinner at a restaurant. Schemas are central in …

Adaptive decision-making requires consideration of objective risks and rewards associated
with each option, as well as subjective preference for risky/safe alternatives. Inaccurate …

Orbitofrontal cortex (OFC) and secondary motor cortex (M2) are both implicated in flexible
reward learning but the conditions that differentially recruit these regions are not fully …

An in-depth investigation of the structure, neuronal mechanisms, and computations of the
frontal lobe that enable higher-level thought. Experts from neurobiology, neuroanatomy …