Antigen loss following CAR‐T cell therapy: Mechanisms, implications, and potential solutions

A Mishra, R Maiti, P Mohan… - European Journal of …, 2024 - Wiley Online Library
Abstract Chimeric Antigen Receptor T‐cell (CAR‐T cell) therapy has emerged as a
groundbreaking immunotherapeutic approach for treating various hematological …

Introducing fluorescence-guided surgery for pediatric Ewing, osteo-, and rhabdomyosarcomas: a literature review

Z Rijs, B Jeremiasse, N Shifai, H Gelderblom, CFM Sier… - Biomedicines, 2021 - mdpi.com
Sarcomas are a rare heterogeneous group of malignant neoplasms of mesenchymal origin
which represent approximately 13% of all cancers in pediatric patients. The most prevalent …

Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR …

Z Li, Y Jiang, J Liu, H Fu, Q Yang… - … Journal of Oncology, 2023 - spandidos-publications.com
Bladder cancer (BC) is a heterogeneous disease, and pyrroline‑5‑carboxylate reductase 1
(PYCR1) can promote the proliferation and invasion of BC cells and accelerate BC …

Specific detection and deletion of the sigma‐1 receptor widely expressed in neurons and glial cells in vivo

Q Liu, Q Guo, LP Fang, H Yao, A Scheller… - Journal of …, 2023 - Wiley Online Library
The chaperon protein sigma‐1 receptor (S1R) has been discovered over 40 years ago.
Recent pharmacological studies using S1R exogenous ligands demonstrated a promising …

Similarities between stem cell niches in glioblastoma and bone marrow: rays of hope for novel treatment strategies

VVV Hira, B Breznik, M Vittori… - … of Histochemistry & …, 2020 - journals.sagepub.com
Glioblastoma is the most aggressive primary brain tumor. Slowly dividing and therapy-
resistant glioblastoma stem cells (GSCs) reside in protective peri-arteriolar niches and are …

Heparin immobilization of tissue engineered xenogeneic small diameter arterial scaffold improve endothelialization

K Tardalkar, T Marsale, N Bhamare… - Tissue Engineering and …, 2022 - Springer
Abstract Background: Autologous vessels graft (Inner diameter< 6 mm) harvesting always
challenged during bypass grafting surgery and its complication shows poor outcome. Tissue …

[HTML][HTML] Delineation of the healthy rabbit heart by immunohistochemistry–A technical note

GM Bürgisser, DM Heuberger, N Schaffner… - Acta histochemica, 2023 - Elsevier
Heart failure poses a big health problem and may result from obesity, smoking, alcohol
and/or growing age. Studying pathological heart tissue demands accurate histological and …

[HTML][HTML] Delineation of the healthy rabbit tonsil by immunohistochemistry–A short communication

GM Bürgisser, DM Heuberger, P Giovanoli… - Acta …, 2023 - Elsevier
Situated in the oral cavity, the rabbit palatine tonsils are part of the mucosal immune system
and help to defend the body against foreign pathogens. Expressed as two oval protrusions …

Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer

AW Kastelein, LMC Vos, JOAM van Baal… - Clinical & Experimental …, 2020 - Springer
Most women with epithelial ovarian cancer (EOC) suffer from peritoneal carcinomatosis
upon first clinical presentation. Extensive peritoneal carcinomatosis has a poor prognosis …

Extracellular-matrix Composite Bioink for 3D bioprinting and molding of small diameter vascular grafts

KR Tardalkar, LR Chaudhari, MN Damle, AA Kawale… - Bioprinting, 2023 - Elsevier
Vascular grafts are used in numerous vascular surgeries around the world, although these
procedures are constrained by vascular graft-related problems and size inconsistencies …