Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis

P Deb, S Sharma, KM Hassan - Pathophysiology, 2010 - Elsevier
Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

Chlorinative stress: an under appreciated mediator of neurodegeneration?

YW Yap, M Whiteman, NS Cheung - Cellular signalling, 2007 - Elsevier
Oxidative stress has been implicated as playing a role in neurodegenerative disorders, such
as ischemic stroke, Alzheimer's, Huntington's, and Parkinson's disease. Persuasive …

Self‐healing and injectable hydrogel for matching skin flap regeneration

X Mao, R Cheng, H Zhang, J Bae, L Cheng… - Advanced …, 2019 - Wiley Online Library
The fabrication of highly biocompatible hydrogels with multiple unique healing abilities for
the whole healing process, for example, multifunctional hydrogels with injectable …

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …

DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Programmed cell death in Parkinson's disease

K Venderova, DS Park - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Parkinson's disease is a debilitating disorder characterized by a progressive loss of
dopaminergic neurons caused by programmed cell death. The aim of this review is to …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Inflammation & apoptosis in spinal cord injury

N Zhang, Y Yin, SJ Xu, YP Wu… - Indian journal of medical …, 2012 - journals.lww.com
Spinal cord injury (SCI) consists of a two-steps process involving a primary mechanical
injury followed by an inflammatory process and apoptosis. Secondary insult is characterized …

[HTML][HTML] Understanding apoptosis in sickle cell anemia patients: Mechanisms and implications

EI Obeagu, NI Ubosi, GU Obeagu, SI Egba, MH Bluth - Medicine, 2024 - journals.lww.com
Sickle cell anemia (SCA) is a hereditary blood disorder characterized by the presence of
abnormal hemoglobin, leading to the formation of sickle-shaped red blood cells. While much …

Apoptosis signaling pathways and lymphocyte homeostasis

G Xu, Y Shi - Cell research, 2007 - nature.com
It has been almost three decades since the term “apoptosis” was first coined to describe a
unique form of cell death that involves orderly, gene-dependent cell disintegration. It is now …

Protective effect of quercetin against oxidative stress-induced cytotoxicity in rat pheochromocytoma (PC-12) cells

D Bao, J Wang, X Pang, H Liu - Molecules, 2017 - mdpi.com
Oxidative stress has been implicated in the pathogenesis of many kinds of
neurodegenerative disorders, particularly Parkinson's disease. Quercetin is a bioflavonoid …