A variety of stressful events, including emotional stress, cause a marked increase in
noradrenaline release in several brain regions, and especially in the hypothalamus …

Classical pharmacological dependence accompanied by euphoria, clinical evidence of
tolerance and escalation of dosage are very rare with the benzodiazepines. However, there …

An electronic skin (e-skin) for the next generation of robots is expected to have biological
skin-like multimodal sensing, signal encoding, and preprocessing. To this end, it is …

SELF-CONTROL Psychology has had a long and stormy relationship with concepts relating
to issues of human agency. Willpower, will, and self-control have all been part of the battle …

To assess the role of serotonin function in the development of panic anxiety, the behavioral
and biochemical responses to the serotonin receptor agonist, m-chlorophenylpiperazine …

Serotonin (5hydroxytryptamine; 5-HT) was first discovered in 1948 in blood platelets and a
few years later in the brain. Since then, investigations of 5-HT involvement in mental …

Radioligand binding studies were used to analyze the interactions of two novel anxiolytics,
buspirone and TVX Q 7821, with a series of 10 neuronal membrane receptor sites …

The old-fashioned doctor, whose departure from the modern medical scene is so greatly
lamented, was amply aware of each patient's per sonality, family, work, and way of life …

GABAkines, or positive allosteric modulators of γ-aminobutyric acid-A (GABA A) receptors,
are used for the treatment of anxiety, epilepsy, sleep, and other disorders. The search for …

Benzodiazepines produce their pharmacological effects by regulating the interaction of
GABA with its recognition site on the GABA A receptor complex. In fact, the anxiolytic effect of …