spotter: a single-nucleotide resolution stochastic simulation model of supercoiling-mediated transcription and translation in prokaryotes
WC Hacker, AH Elcock - Nucleic acids research, 2023 - academic.oup.com
Stochastic simulation models have played an important role in efforts to understand the
mechanistic basis of prokaryotic transcription and translation. Despite the fundamental …
mechanistic basis of prokaryotic transcription and translation. Despite the fundamental …
Protein Translation Can Fluidize Bacterial Cytoplasm
The cytoplasm of bacterial cells is densely packed with highly polydisperse macromolecules
that exhibit glassy dynamics. Research has revealed that metabolic activities in living cells …
that exhibit glassy dynamics. Research has revealed that metabolic activities in living cells …
Transcription-translation coupling: Traveling a road under construction
S Klumpp - Biophysical Journal, 2023 - cell.com
The genetic information stored in DNA is read out in two steps: transcription and translation.
The two steps are carried out by two large molecular machines, RNA polymerases (RNAPs) …
The two steps are carried out by two large molecular machines, RNA polymerases (RNAPs) …