[HTML][HTML] New insights into the pathogenesis of Peyronie's disease: A narrative review

DV Krakhotkin, VA Chernylovskyi, A Mottrie… - Chronic diseases and …, 2020 - Elsevier
Peyronie's disease (PD) is a benign, progressive fibrotic disorder characterized by scar or
plaques within the tunica albuginea (TA) of the penis. This study provides new insights into …

Current trends in non‐surgical management of Peyronie's disease—A narrative review

A Kozub, A Suleja, M Chłosta, A Kupilas, B Pradere… - …, 2024 - Wiley Online Library
Peyronie's disease (PD) is a connective tissue disorder affecting the tunica albuginea. It can
cause pain and penile deformation, and its prevalence increases with age. Although surgery …

[HTML][HTML] Tissue anisotropy and collagenomics in porcine penile tunica albuginea: Implications for penile structure-function relationships and tissue engineering

BJ Bielajew, RC Nordberg, JC Hu, KA Athanasiou… - Acta Biomaterialia, 2023 - Elsevier
The tunica albuginea (TA) of the penis is an elastic layer that serves a structural role in
penile erection. Disorders affecting the TA cause pain, deformity, and erectile dysfunction …

Low-intensity laser diode plus extracorporeal shock wave therapy: a new treatment strategy in the management of Peyronie's disease

L Dell'Atti, P Ronchi - World Journal of Urology, 2023 - Springer
Purpose To assess the clinical effectiveness of extra corporeal shockwave therapy (ESWT)
administration compared with ESWT plus a low-intensity laser diode therapy (LILDT) in the …

Penile prosthesis implantation is safe and effective in Peyronie's disease patients with and without erectile dysfunction

I Moncada, P Krishnappa, C Zaccaro, A Fraile… - International journal of …, 2024 - nature.com
Penile prosthesis (PP) is the mainstay of treatment in Peyronie's disease (PD) with co-
existent refractory erectile dysfunction (ED). This study aimed to assess the clinical …

Intratunical injection of rat-derived bone marrow mesenchymal stem cells prevents fibrosis and is associated with increased Smad7 expression in a rat model of …

W Wang, W Ding, X Zhang, S Wu, T Yu, X Cui… - Stem Cell Research & …, 2022 - Springer
Objective Peyronie's disease (PD) is a fibrotic disorder of the penis, but effective treatments
are lacking. Here, we observed the effects of rat-derived bone marrow mesenchymal stem …

The influence of indentation deformity on outcomes with intralesional collagenase Clostridium histolyticum monotherapy for Peyronie's disease

MJ Ziegelmann, D Heslop, M Houlihan, P Bajic, S Helo… - Urology, 2020 - Elsevier
Objective To identify patient-specific factors associated with patient-reported improvements
in functional outcomes after intralesional Collagenase Clostridium histolyticum (CCH) for …

Molecular and spatial signatures of human and rat corpus cavernosum physiopathological processes at single-cell resolution

Y Yin, Y Chen, J Xu, B Liu, Y Zhao, X Tan, M Xiao… - Cell Reports, 2024 - cell.com
The composition and cellular heterogeneity of the corpus cavernosum (CC)
microenvironment have been characterized, but the spatial heterogeneity at the molecular …

Conservative therapy for Peyronie's disease: a contemporary review of the literature

A Yousif, C Natale, WJG Hellstrom - Current Urology Reports, 2021 - Springer
Abstract Purpose of Review To analyze the literature on current conservative treatment
options for Peyronie's disease (PD). Recent Findings Conservative therapy with intralesional …

Are finasteride-related penile curvature/Peyronie's disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both …

N Schifano, P Capogrosso, L Boeri, G Fallara… - International Journal of …, 2023 - nature.com
A limited number of studies have described patients on finasteride showing findings which
were consistent with Peyronie's disease (PD). We aimed to detect a pharmacovigilance …