L Morin, K Johnell, ML Laroche, J Fastbom… - Clinical …, 2018 - Taylor & Francis
Objective Polypharmacy is the concomitant use of several drugs by a single person, and it increases the risk of adverse drug-related events in older adults. Little is known about the …
L Ye, J Yang-Huang, CB Franse, T Rukavina… - BMC geriatrics, 2022 - Springer
Background Polypharmacy can be defined as using five or more medications simultaneously.“Medication-related problems”, an extension of polypharmacy, includes …
Background Polypharmacy is common among older adults. However, little is known about the composition of polypharmacy: which are the most frequently used drugs, and how much …
Polypharmacy is very common in older patients and may be associated with drug-drug interactions. Hepatic cytochrome P450 (notably 3A4 subtype, CYP3A4) is a key enzyme …
M Meinshausen, A Rieckert, A Renom-Guiteras… - BMC geriatrics, 2017 - Springer
Background Platelet aggregation inhibitors (PAI) are among the most frequently prescribed drugs in older people, though evidence about risks and benefits of their use in older adults is …
LE Davies, A Kingston, A Todd, B Hanratty - PLoS One, 2021 - journals.plos.org
Background Polypharmacy is potentially harmful and under-researched amongst the fastest growing subpopulation, the very old (aged≥ 85). We aimed to characterise polypharmacy …
L Degli Esposti, V Perrone, C Veronesi… - … medical research and …, 2018 - Taylor & Francis
Objective: The purpose of this study was to assess the changes in adherence to treatment, in patients who switched from perindopril and/or amlodipine as a monotherapy (single-pill …
A Neumann-Podczaska, S Tobis, D Antimisiaris… - International journal of …, 2022 - mdpi.com
Polypharmacy is a challenging issue in geriatrics. The aim of the study was to characterize correlates of polypharmacy in the PolSenior project. The PolSenior project, was a …
A Strampelli, F Cerreta, K Vučić - British journal of clinical …, 2020 - Wiley Online Library
Aims The aim of this study was to elucidate drug prescription patterns in older European people with the objective to support regulatory contextualisation of (1) the suitability of …