Pharmacological and Toxicological Effects of Catha edulis F. (Khat)

E Engidawork - Phytotherapy Research, 2017 - Wiley Online Library
Khat chewing is deeply rooted in the culture and tradition of communities in khat belt
countries, and its consumption is spread to other countries through the suitcase trade. The …

Khat use and appetite: an overview and comparison of amphetamine, khat and cathinone

AM Lemieux, B Li, M al'Absi - Journal of ethnopharmacology, 2015 - Elsevier
Ethnopharmacological relevance To understand the role of khat (Catha edulis) use on the
aberrations in appetite and weight which are common comorbidities for khat and other …

Histopathological Evaluation of Annona muricata in TAA-Induced Liver Injury in Rats

MH Al-Medhtiy, AA Jabbar, SH Shareef, IAA Ibrahim… - Processes, 2022 - mdpi.com
This research in vivo assessed the impact of the ethanolic extract of Annona muricata (A.
muricata) on the histopathology, immunohistochemistry, and biochemistry of thioacetamide …

[HTML][HTML] Garcinia mangostana peel extracts exhibit hepatoprotective activity against thioacetamide-induced liver cirrhosis in rats

WN Abood, SW Bradosty, FK Shaikh… - Journal of Functional …, 2020 - Elsevier
The study in vivo evaluated the influence of ethanolic extract of G. mangostana peel on the
histology, immunohistochemistry, and biochemistry of thioacetamide (TAA) induced liver …

Facilitated and controlled strontium ranelate delivery using GCS-HA nanocarriers embedded into PEGDA coupled with decortication driven spinal regeneration

CW Chiang, CH Chen, YB Manga… - International journal …, 2021 - Taylor & Francis
Background and Purpose Strontium ranelate (SrR) is an oral pharmaceutical agent for
osteoporosis. In recent years, numerous unwanted side effects of oral SrR have been …

Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice

VK Mwaeni, JN Nyariki, N Jillani, G Omwenga… - BMC Pharmacology and …, 2021 - Springer
Background Arsenic poisoning affects millions of people. The inorganic forms of arsenic are
more toxic. Treatment for arsenic poisoning relies on chelation of extracellularly circulating …

Khat chewing increases the risk for developing chronic liver disease: A hospital‐based case–control study

SMS Orlien, I Sandven, NB Berhe, NY Ismael… - …, 2018 - Wiley Online Library
The chewing of the leaves of Catha edulis (khat) has been implicated in the development of
liver disease, but no controlled observations have been undertaken. The objective of the …

Unexplained chronic liver disease in Ethiopia: a cross-sectional study

SMS Orlien, NY Ismael, TA Ahmed, N Berhe… - BMC …, 2018 - Springer
Abstract Background Hepatitis B virus (HBV) infection is assumed to be the major cause of
chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological …

Mutagenicity and genotoxicity effects of Verbena officinalis leaves extract in Sprague-Dawley Rats

AH Fateh, Z Mohamed, Z Chik, A Alsalahi… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Traditionally, Verbena officinalis L. has been
used for reproductive and gynaecological purposes. However, the mutagenicity and …

Coenzyme Q10 nullified khat-induced hepatotoxicity, nephrotoxicity and inflammation in a mouse model

C Kennedy, P Okanya, JN Nyariki, P Amwayi, N Jillani… - Heliyon, 2020 - cell.com
Ethnopharmacological relevance The consumption of khat (Catha Edulis, Forsk) is on the
rise despite the much publicized associated deleterious health effects. How chemicals …