Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades

AK Hubbard, R Rothlein - Free radical biology and medicine, 2000 - Elsevier
The collective interaction between cells is, in part, mediated by different families of adhesion
molecules. Intercellular adhesion molecules (ICAMs) are structurally related members of the …

Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications

JA Rowe, A Claessens, RA Corrigan… - Expert reviews in …, 2009 - cambridge.org
Severe malaria has a high mortality rate (15–20%) despite treatment with effective
antimalarial drugs. Adjunctive therapies for severe malaria that target the underlying disease …

Rapid switching to multiple antigenic and adhesive phenotypes in malaria

DJ Roberts, Craig, AR Berendt, R Pinches, G Nash… - Nature, 1992 - nature.com
ADHESION of parasitized erythrocytes to post-capillary venular endothelium1or uninfected
red cells'2–4 is strongly implicated in the pathogenesis of severe Plasmodlum faldparum …

Regulation of myeloid development and function by colony stimulating factors

DR Barreda, PC Hanington, M Belosevic - Developmental & Comparative …, 2004 - Elsevier
The colony-stimulating factors (CSFs) are a group of cytokines central to the hematopoiesis
of blood cells, the modulation of their functional responses, as well as the maintenance of …

FK-506-and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

SJ O'Keefe, J Tamura, RL Kincaid, MJ Tocci, EA O'Neill - Nature, 1992 - nature.com
ANTIGEN recognition by the T-cell receptor (TCR) initiates events including lymphokine
gene transcription1, particularly interleukin-2, that lead to T-cell activation. The …

Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells

BC Urban, DJP Ferguson, A Pain, N Willcox… - Nature, 1999 - nature.com
The malaria parasite Plasmodium falciparum is one of the most successful human
pathogens. Specific virulence factors remain poorly defined, although the adhesion of …

Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway

LR Languino, J Plescia, A Duperray, AA Brian, EF Plow… - Cell, 1993 - cell.com
Leukocyte traffic in immune-inflammatory responses requires regulated adhesion of
leukocyte subsets to vascular endothelium. We show that fibrlnogen or normal human …

The dengue virus nonstructural-1 protein (NS1) generatesantibodies to common epitopes on human blood clotting, integrin/adhesin proteins and binds to …

AKI Falconar - Archives of virology, 1997 - Springer
Antibody responses generated by mice to the dengue-2 virus NS1 protein (D-2V NS1) were
influenced by MHC class II (IA) haplotype but each antiserum cross-reacted with human …

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

A Claessens, Y Adams, A Ghumra… - Proceedings of the …, 2012 - National Acad Sciences
Cerebral malaria is the most deadly manifestation of infection with Plasmodium falciparum.
The pathology of cerebral malaria is characterized by the accumulation of infected …

Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions

M Singh, M Thakur, M Mishra, M Yadav, R Vibhuti… - Immunology letters, 2021 - Elsevier
Abstract Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied
inducible cell adhesion molecules which is responsible for several immune functions like T …