Following the history of organic chemistry, studies on relations between chemical (and later
physicochemical) properties and the structure of chemical species in question are the heart …

The epithelium-mesenchymal transition (EMT) is an important process of cell plasticity,
consisting in the loss of epithelial identity and the gain of mesenchymal characteristics …

The highly regioselective C6–H hydroxylalkylation of purines and purine nucleosides within
10 min via the α-C (sp3)–H functionalization of alcohols at room temperature is reported …

Cobamides such as vitamin B12 are structurally conserved, cobalt-containing tetrapyrrole
biomolecules that have essential biochemical functions in all domains of life. In …

Computed association energies and dissected nucleus-independent chemical shifts (NICS)
document the mutual enhancement (or reduction) of intermolecular interactions and the …

Heterocycles containing one or more amidine moieties {–NH–C (R) N–} such as adenine
and its building blocks, imidazole, 4-aminopyrimidine, and purine, are excellent examples of …

The geometry-based HOMA (Harmonic Oscillator Model of Aromaticity) descriptor, based on
the reference compounds of different delocalizations of n-and π-electrons, can be applied to …

The use of enzymes for the synthesis of nucleoside analogues offers several advantages
over multistep chemical methods, including chemo‐, regio‐and stereoselectivity as well as …

Intramolecular resonance-assisted hydrogen bonds (RAHBs) are stronger than conventional
hydrogen bonds (HBs) thanks to the extra stabilization connected with the partial …

The purine molecular structure consists of fused pyrimidine and imidazole rings. Purines are
main pieces that conform the structure of nucleic acids which rule the inheritance processes …