The innate immune system is the first line of host defense against infection and is comprised
of humoral and cellular mechanisms that recognize potential pathogens within minutes or …

The lectin pathway of the complement system has a pivotal role in the defense against
infectious organisms. After binding of mannan-binding lectin (MBL), ficolins or collectin 11 to …

Although some evidence showed the activation of complement systems in COVID-19
patients, proinflammatory status and lectin pathway remain unclear. Thus, the present study …

Abstract Context: Cuscuta reflexa Roxb.(Cuscutaceae) has been used traditionally for
treating sore knees and kidney problems, but its efficacy has not been scientifically …

Addressing a major condition affecting millions worldwide, this source compiles the most
practical and groundbreaking research on the etiology, assessment, and treatment of Age …

MASP-2 is a key protein of the lectin pathway of complement system. Several MASP2
polymorphisms were associated with MASP-2 serum levels or functional activity. Here we …

Chagas disease (CD) is caused by Trypanosoma cruzi, whose sugar moieties are
recognized by mannan binding lectin (MBL), a soluble pattern-recognition molecule that …

Background Rheumatic fever (RF) is the result of an autoimmune response to pharyngitis
caused by infection with Streptococcus pyogenes. RF is most prevalent in Africa and the …

Increasing evidence over the past two decades points to a pivotal role for immune
mechanisms in age-related macular degeneration (AMD) pathobiology. In this chapter, we …

Background Mannan-binding lectin-associated serine protease 2 (MASP-2) is a key protein
of the lectin pathway of complement. MASP-2 levels have been associated with different …