New Delhi metallo-β-lactamase (NDM) carbapenemase has been considered a global
threat due to its worldwide widespread in recent years. In Portugal, a very low number of …

Klebsiella pneumoniae is a major pathogen implicated in nosocomial infections. Extended-
spectrum β-lactamase (ESBL)-producing K. pneumoniae isolates are a public health …

While antibiotic resistance is rising to dangerously high levels, resistance mechanisms are
spreading globally among diverse bacterial species. The emergence of antibiotic-resistant …

Carbapenemases, a class of enzymes specialized in the hydrolysis of carbapenems,
represent a significant threat to global public health. These enzymes are classified into …

The carbapenem-resistant Enterobacterales (CRE) strains have been identified by the World
Health Organization as critical priority pathogens in research and development of …

Klebsiella pneumoniae (Kp) bacteria are an increasing threat to public health and represent
one of the most concerning pathogens involved in life-threatening infections and …

Klebsiella pneumoniae is considered an opportunistic pathogen frequently involved with
healthcare-associated infections. The genome of K. pneumoniae is versatile, harbors …

Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CR Kp) is the most
prevalent carbapenem-resistant Enterobacterales in the United States. We evaluated CR Kp …

Klebsiella spp. is a relevant pathogen that can present acquired resistance to almost all
available antibiotics, thus representing a serious threat for public health. While most studies …

The combination of ceftazidime/avibactam (CZA) is a novel β-lactam/β-lactamase inhibitor
with activity against Klebsiella pneumoniae carbapenemase (KPC)-producing …