Endogenous noncoding circular RNAs (circRNAs) have gained attention for their
involvement in carcinogenesis, but their expression pattern in breast cancer has remained …

Background Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent
gastrointestinal malignancies with high mortality. Circular RNAs (CircRNAs) have become a …

Esophageal cancer is associated with a dismal prognosis. The armamentarium of approved
drugs is focused on chemotherapy with modest therapeutic benefit. Recently, checkpoint …

Transcriptional coregulators drive gene regulatory decisions in the transcriptional space.
Although transcription factors including all nuclear receptors provide a docking platform for …

It has become clearer that advanced cancer, especially advanced breast cancer, is an
entirely displayed pathological system that is much more complex than previously …

Using chip array assays, we identified differentially expressed genes via a comparison
between luminal A breast cancer subtype and normal mammary ductal cells from healthy …

Ligand-dependent corepressor (LCoR) is a transcriptional repressor of ligand-activated
estrogen receptors (ERs) and other transcription factors that acts both by recruiting histone …

Cancer cells switch their metabolism toward glucose metabolism to sustain their
uncontrolled proliferation. Consequently, glycolytic intermediates are diverted into the …

Using age of female sexual maturation as a biomarker, we previously identified nuclear
receptor interacting protein 1 (Nrip1) as a candidate gene that may regulate aging and …

Background Nuclear receptor-interacting protein 1 (NRIP1), also named NR140, has been
observed differentially express in multiple cancers, but the expression levels and the …