Metabolomic fingerprinting for the detection of early-stage lung cancer: from the genome to the metabolome
The five-year survival rate of lung cancer patients is very low, mainly because most newly
diagnosed patients present with locally advanced or metastatic disease. Therefore, early …
diagnosed patients present with locally advanced or metastatic disease. Therefore, early …
Metabolomics of asthma, COPD, and asthma-COPD overlap: an overview
S Dasgupta, N Ghosh, P Bhattacharyya… - Critical Reviews in …, 2023 - Taylor & Francis
The two common progressive lung diseases, asthma and chronic obstructive pulmonary
disease (COPD), are the leading causes of morbidity and mortality worldwide. Asthma …
disease (COPD), are the leading causes of morbidity and mortality worldwide. Asthma …
Bioinformatics analysis of hypoxia associated genes and inflammatory cytokine profiling in COPD-PH
P Choudhury, S Dasgupta, A Kar, S Sarkar… - Respiratory …, 2024 - Elsevier
Pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) is
associated with worse clinical outcomes and decreased survival rates. In absence of …
associated with worse clinical outcomes and decreased survival rates. In absence of …
Metabolic pathways, genomic alterations, and post-translational modifications in pulmonary hypertension and cancer as therapeutic targets and biomarkers
X Zhang, Z Fu, H Wang, L Sheng - Frontiers in Pharmacology, 2024 - frontiersin.org
Background Pulmonary hypertension (PH) can lead to right ventricular hypertrophy,
significantly increasing mortality rates. This study aims to clarify PH-specific metabolites and …
significantly increasing mortality rates. This study aims to clarify PH-specific metabolites and …
Discovery of novel metabolic signatures for early identification of women at risk of developing gestational hypertension
Introduction Gestational hypertension (GH) is defined as the presence of systolic blood
pressure (BP)≥ 140 mm Hg and/or diastolic BP≥ 90 mm Hg, measured at least 4 h apart …
pressure (BP)≥ 140 mm Hg and/or diastolic BP≥ 90 mm Hg, measured at least 4 h apart …
Metabolomics in Pulmonary Hypertension—A Useful Tool to Provide Insights into the Dark Side of a Tricky Pathology
PP Bassareo, M D'Alto - International Journal of Molecular Sciences, 2023 - mdpi.com
Pulmonary hypertension (PH) is a multifaceted illness causing clinical manifestations like
dyspnea, fatigue, and cyanosis. If left untreated, it often evolves into irreversible pulmonary …
dyspnea, fatigue, and cyanosis. If left untreated, it often evolves into irreversible pulmonary …
Identification and molecular modelling of potential drugs targeting the genes involved in the progression of lung cancer in patients with idiopathic pulmonary fibrosis
S Dasgupta - Gene Reports, 2024 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is characterized by progressive fibrosis in
the lung parenchyma. Given the fact that IPF patients are at significant risk of developing …
the lung parenchyma. Given the fact that IPF patients are at significant risk of developing …