The neurobiological processes by which ethanol seeking and consumption are established
and maintained are thought to involve areas of the brain that mediate motivated behavior …

Many studies have used voluntary ethanol consumption by animals to assess the influence
of genetic and environmental manipulations on ethanol drinking. However, the relationship …

High and low alcohol preference (HAP and LAP, respectively) mice were created by 10
generations of bidirectional selection for differences in two-bottle choice alcohol …

Upregulation of β2 subunit-containing (β2*) nicotinic acetylcholine receptors (nAChRs) is
implicated in several aspects of nicotine addiction, and menthol cigarette smokers tend to …

Background: Repeated alcohol administration alters nucleus accumbens (NAC) basal
glutamate content and sensitizes the capacity of alcohol to increase NAC extracellular …

Alcohol's positive and negative motivational effects are believed to be important influences
on alcohol-seeking behavior and, therefore, key factors among the many and varied causes …

Abstract Rationale The Scheduled High Alcohol Consumption (SHAC) binge drinking model
is a simple, partial murine model with which to investigate some of the neurobiological …

G protein-gated inwardly rectifying potassium (GIRK) channels are critical regulators of
neuronal excitability and can be directly activated by ethanol. Constitutive deletion of the …

Chronic intravenous drug self-administration in rodents is a useful procedure for predicting
the abuse liability of novel drugs in humans, for evaluating candidate treatments for drug …

Background Glucagon‐like peptide 1 (GLP‐1) receptor agonists have been shown to
decrease ethanol (EtOH) drinking in rodent assays. The GLP‐1 system also powerfully …