Melatonin and health: insights of melatonin action, biological functions, and associated disorders

SB Ahmad, A Ali, M Bilal, SM Rashid, AB Wani… - Cellular and Molecular …, 2023 - Springer
Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

Melatonin: buffering the immune system

A Carrillo-Vico, PJ Lardone… - International journal of …, 2013 - mdpi.com
Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …

Protective role of melatonin in cardiac ischemia‐reperfusion injury: From pathogenesis to targeted therapy

H Zhou, Q Ma, P Zhu, J Ren, RJ Reiter… - Journal of pineal …, 2018 - Wiley Online Library
Acute myocardial infarction (MI) is a major cause of mortality and disability worldwide. In
patients with MI, the treatment option for reducing acute myocardial ischemic injury and …

Melatonin in health and disease: A perspective for livestock production

ZE Contreras-Correa, RD Messman, RM Swanson… - Biomolecules, 2023 - mdpi.com
Mounting evidence in the literature indicates an important role of endogenous and
exogenous melatonin in driving physiological and molecular adaptations in livestock …

Effects of melatonin on oxidative stress, and resistance to bacterial, parasitic, and viral infections: a review

JR Vielma, E Bonilla, L Chacín-Bonilla, M Mora… - Acta tropica, 2014 - Elsevier
Melatonin, a hormone secreted by the pineal gland, works directly and indirectly as a free
radical scavenger. Its other physiological or pharmacological activities could be dependent …

Potential relevance of melatonin against some infectious agents: a review and assessment of recent research

E Kotb Elmahallawy, J Ortega Luque… - Current medicinal …, 2015 - ingentaconnect.com
Melatonin, a tryptophan-derived neurohormone found in animals, plants, and microbes,
participates in various biological and physiological functions. Among other properties …

Nano-Encapsulated Melatonin: A Promising Mucosal Adjuvant in Intranasal Immunization against Chronic Experimental T. gondii Infection

DE Said, EI Amer, E Sheta, S Makled, HE Diab… - Tropical Medicine and …, 2022 - mdpi.com
Melatonin (MLT) is now emerging as one of the universally accepted immunostimulators
with broad applications in medicine. It is a biological manipulator of the immune system …

Seasonal modulation of immunity by melatonin and gonadal steroids in a short day breeder goat Capra hircus

S Ghosh, AK Singh, C Haldar - Theriogenology, 2014 - Elsevier
Role of melatonin in regulation of immunity and reproduction has never been studied in
detail in goats. The aim of the present study was to explore hormonal regulation of immunity …

Melatonin as a multifunctional modulator: emerging insights into its role in health, reproductive efficiency, and productive performance in livestock

A Afzal - Frontiers in Physiology, 2024 - frontiersin.org
Melatonin, a pleiotropic hormone plays a vital role in enhancing livestock performance not
only by regulating circadian rhythms but also by exhibiting antioxidant, immunomodulatory …

Melatonin enhances responsiveness to Dichelobacter nodosus vaccine in sheep and increases peripheral blood CD4 T lymphocytes and IgG-expressing B …

A Ramos, MP Míguez, S Morgado… - Veterinary immunology …, 2018 - Elsevier
The immunomodulatory functions mediated by melatonin support its use as vaccine
adjuvant. Previously, we have demonstrated that melatonin enhances antibody responses in …