Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa

AJ Kunz Coyne, A El Ghali, D Holger, N Rebold… - Infectious diseases and …, 2022 - Springer
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa
isolates are frequent causes of serious nosocomial infections that may compromise the …

The revival of aztreonam in combination with avibactam against metallo-β-lactamase-producing Gram-negatives: a systematic review of in vitro studies and clinical …

C Mauri, AE Maraolo, S Di Bella, F Luzzaro, L Principe - Antibiotics, 2021 - mdpi.com
Infections caused by metallo-β-lactamase (MBL)-producing Enterobacterales and
Pseudomonas are increasingly reported worldwide and are usually associated with high …

β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospects

KA Glen, IL Lamont - Pathogens, 2021 - mdpi.com
Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …

Treatment options for K. pneumoniae, P. aeruginosa and A. baumannii co-resistant to carbapenems, aminoglycosides, polymyxins and tigecycline: an approach …

S Karakonstantis, EI Kritsotakis, A Gikas - Infection, 2020 - Springer
The management of carbapenem-resistant infections is often based on polymyxins,
tigecycline, aminoglycosides and their combinations. However, in a recent systematic …

New Drugs for the Treatment of Pseudomonas aeruginosa Infections with Limited Treatment Options: A Narrative Review

AR Losito, F Raffaelli, P Del Giacomo, M Tumbarello - Antibiotics, 2022 - mdpi.com
P. aeruginosa is still one of the most threatening pathogens responsible for serious hospital-
acquired infections. It is intrinsically resistant to many antimicrobial agents and additional …

Guidelines for the diagnosis, treatment, prevention and control of infections caused by carbapenem-resistant gram-negative bacilli

M Zeng, J Xia, Z Zong, Y Shi, Y Ni, F Hu, Y Chen… - Journal of Microbiology …, 2023 - Elsevier
The dissemination of carbapenem-resistant Gram-negative bacilli (CRGNB) is a global
public health issue. CRGNB isolates are usually extensively drug-resistant or pandrug …

Review of Ceftazidime-Avibactam for the Treatment of Infections Caused by Pseudomonas aeruginosa

GL Daikos, CA da Cunha, GM Rossolini, GG Stone… - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that causes a range
of serious infections that are often challenging to treat, as this pathogen can express multiple …

Pharmacokinetic/pharmacodynamic analysis of continuous-infusion fosfomycin in combination with extended-infusion cefiderocol or continuous-infusion ceftazidime …

M Gatti, M Giannella, M Rinaldi, P Gaibani, P Viale… - Antibiotics, 2022 - mdpi.com
Objectives: To perform a pharmacokinetic/pharmacodynamic (PK/PD) analysis of continuous-
infusion (CI) fosfomycin combined with extended-infusion (EI) cefiderocol or CI ceftazidime …

The impact of COVID-19 on the profile of hospital-acquired infections in adult intensive care units

A Despotovic, B Milosevic, A Cirkovic, A Vujovic… - Antibiotics, 2021 - mdpi.com
Hospital-acquired infections (HAIs) are a global public health concern. As the COVID-19
pandemic continues, its contribution to mortality and antimicrobial resistance (AMR) grows …

Effectiveness of ceftazidime-avibactam for the treatment of infections due to Pseudomonas aeruginosa

L Corbella, J Boán, R San-Juan… - International journal of …, 2022 - Elsevier
Background Clinical experience with ceftazidime-avibactam (CAZ-AVI) for treatment of
infections due to multidrug or extremely resistant (MDR/XDR) Pseudomonas aeruginosa (P …