Selective receptor-targeting peptide based agents have attracted considerable attention in
molecular imaging of tumor cells that overexpress corresponding peptide receptors due to …

Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …

Human cancer cells overexpress many peptide receptors as molecular targets.
Radiolabeled peptides that bind with high affinity and specificity to the receptors on tumor …

Purpose Gallium-68 is a metallic positron emitter with a half-life of 68 min that is ideal for the
in vivo use of small molecules, such as [68 Ga-DOTA, Tyr 3] octreotide, in the diagnostic …

Identified in 1973, somatostatin (SST) is a cyclic hormone peptide with a short biological half-
life. Somatostatin receptors (SSTRs) are widely expressed in the whole body, with five …

Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc
imaging agents continues to be in demand. This overview discusses basic principles of …

Two bombesin analogs, Demobesin 4 and Demobesin 1, were characterized in vitro as
gastrin-releasing peptide (GRP) receptor agonist and antagonist, respectively, and were …

An Erratum has been published for this article in Medicinal Research Reviews 2004; 24: 685–
686. Small synthetic receptor‐binding peptides are the agents of choice for diagnostic …

Overexpressed neuropeptide receptors allow tumor visualization using eg radiolabeled
peptidic receptor ligands and positron emission tomography (PET) or single photon …

Demobesin 1 is a potent new GRP-R-selective bombesin (BN) analogue containing an open
chain tetraamine chelator for stable technetium-99m binding. Following a convenient …