Management of moderate to severe traumatic brain injury: an update for the intensivist

G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Perihematomal edema after intracerebral hemorrhage: an update on pathogenesis, risk factors, and therapeutic advances

Y Chen, S Chen, J Chang, J Wei, M Feng… - Frontiers in …, 2021 - frontiersin.org
Intracerebral hemorrhage (ICH) has one of the worst prognoses among patients with stroke.
Surgical measures have been adopted to relieve the mass effect of the hematoma, and …

The European guideline on management of major bleeding and coagulopathy following trauma

R Rossaint, A Afshari, B Bouillon, V Cerny… - Critical Care, 2023 - Springer
Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …

Moderate and severe traumatic brain injury

CP Robinson - Continuum: lifelong learning in neurology, 2021 - journals.lww.com
PURPOSE OF REVIEW Traumatic brain injury (TBI) encompasses a group of
heterogeneous manifestations of a disease process with high neurologic morbidity and, for …

Management of traumatic brain injury: a narrative review of current evidence

MD Wiles - Anaesthesia, 2022 - Wiley Online Library
Globally, approximately 70 million people sustain traumatic brain injury each year and this
can have significant physical, psychosocial and economic consequences for patients, their …

AUS-TBI: the Australian health Informatics approach to predict outcomes and monitor intervention efficacy after moderate-to-severe traumatic brain injury

M Fitzgerald, J Ponsford, NA Lannin… - Neurotrauma …, 2022 - liebertpub.com
Predicting and optimizing outcomes after traumatic brain injury (TBI) remains a major
challenge because of the breadth of injury characteristics and complexity of brain …

Development of traumatic brain injury associated intracranial hypertension prediction algorithms: a narrative review

R McNamara, S Meka, J Anstey, D Fatovich… - Journal of …, 2023 - liebertpub.com
Traumatic intracranial hypertension (tIH) is a common and potentially lethal complication of
moderate to severe traumatic brain injury (m-sTBI). It often develops with little warning and is …

The emerging role of exosomes in communication between the periphery and the central nervous system

W Han, H Zhang, L Feng, R Dang, J Wang, C Cui… - MedComm, 2023 - Wiley Online Library
Exosomes, membrane‐enclosed vesicles, are secreted by all types of cells. Exosomes can
transport various molecules, including proteins, lipids, functional mRNAs, and microRNAs …

The Australian Traumatic Brain Injury Initiative: statement of working principles and rapid review of methods to define data dictionaries for neurological conditions

MK Bagg, AJ Hicks, SC Hellewell, JL Ponsford… - Neurotrauma …, 2024 - liebertpub.com
The Australian Traumatic Brain Injury Initiative (AUS-TBI) aims to develop a health
informatics approach to collect data predictive of outcomes for persons with moderate …

Targets of neuroprotection and review of pharmacological interventions in traumatic brain injury

MI Hiskens - Journal of Pharmacology and Experimental …, 2022 - ASPET
Traumatic brain injury (TBI) is a major contributor to disability and death worldwide, and
manifests in cognitive, behavioral, and motor impairment. Although there have been …