Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Immune cells in the placental bed are important for adequate development of the placental
bed. The most prominent immune cells in the placental bed early in pregnancy are uterine …

Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

Cytokines are small signaling proteins that have central roles in inflammation and cell
survival. In the half-century since the discovery of the first cytokines, the interferons, over fifty …

Extravillous trophoblast remodeling of the uterine spiral arteries is essential for promoting
blood flow to the placenta and fetal development, but little is known about the regulation of …

Interleukin 11 (IL11) is an elusive member of the IL6 family of cytokines. While initially
thought to be a haematopoietic and cytoprotective factor, more recent data show instead that …

Preeclampsia (PE) is a disease that is unique to pregnancy and affects multiple systems. It
can lead to maternal and perinatal mortality. The precise etiology of PE is unclear. Patients …

Goulopoulou Vascular Changes in Preeclampsia 1067 are increased in placental and
vascular tissues from women with preeclampsia. Systemic pharmacological inhibition of …

Mounting evidence has revealed that impaired spiral artery remodeling, placental
dysfunction, and inadequate trophoblast invasion are closely correlated with the etiology …

Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …