Slices of developing brain tissue can be grown for several weeks as socalled organotypic
slice cultures. Here we summarize and review studies using hippocampal slice cultures to …

The nervous system of mammals retains throughout the animals' life-span the ability to
modify the number, nature, and level of activity of its synapses. Synaptic plasticity is most …

The commissural connections of the hippocampal formation have been analyzed in the
monkey (Macaca fascicularis) using both anterograde and retrograde labeling techniques …

Morphological data on structures of the principal limbic circuit show that they constitute a
complex, hierarchically organized system, and that this is indeed a system with important …

Two markers of neuronal plasticity were used to compare the response of the human central
nervous system to neuronal loss resulting from Alzheimer's disease with the response of rats …

Recently discovered neocortical equivalents in anamniotes and certain patterns of
interspecific variability in brain organization provide new insights into evolutionary and …

This study examined the cellular and connective organization of hippocampal tissue taken
from 6–8‐day‐old rats and cultured by the roller tube technique for 3–6 weeks. In the …

In response to a central nervous system trauma surviving neurons reorganize their
connections and form new synapses that replace those lost by the lesion. A well established …

ABSTRACT A lesion-induced formation of an abnormal projection of hippocampal mossy
fiber collaterals to the molecular layer of the fascia dentata was studied in rats. Both …

Although several studies of Alzheimer's disease suggest that the frequency of neuritic
plaques in the cerebral cortex is correlated with the severity of dementia and with reduction …