In this article, we will review recent progress in elucidating the mechanisms that regulate
phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and discuss advances in …

Lipid phosphates initiate key signaling cascades in cell activation. Lysophosphatidate (LPA)
and sphingosine 1‐phosphate (S1P) are produced by activated platelets. LPA is also formed …

Identification and characterization of anion channel genes in plants represent a goal for a
better understanding of their central role in cell signaling, osmoregulation, nutrition, and …

Lipid phosphate phosphatases (LPPs) are a group of enzymes that belong to a
phosphatase/phosphotransferase family. Mammalian LPPs consist of three isoforms: LPP1 …

Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are potent biologically
active lipid mediators that exert a wide range of cellular effects through specific G protein …

We have identified a novel, conserved phosphatase sequence motif, KXXXXXXRP‐(X12‐
54)‐PSGH‐(X31‐54))‐SRXXXXX HXXXD, that is shared among several lipid phosphatases …

Platelets are known to store a large amount of the bioactive lipid molecule sphingosine 1-
phosphate (S1P) and to release it into the plasma in a stimuli-dependent manner …

Phosphatidate phosphohydrolase (PAP) 1 was first identified as being involved in
glycerolipid synthesis (1). A second PAP activity (PAP-2) was subsequently characterized in …

Phospholipids and sphingolipids play critical roles in signal transduction, intracellular
membrane trafficking, and control of cell growth and survival. We discuss recent progress in …

Distinct, structurally different forms of sn-1, 2-diacylglycerol are found in cells, these are
polyunsaturated, mono-or di-unsaturated and saturated. The pathways that generate or …